Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5958724 | 0.90 | TSHR (0.46) | CYP3A4TSHRALDH1A1MAPK1ALOX15 | |
| SCHEMBL297990 | 0.85 | CYP3A4 (0.42) | CYP3A4TSHRALDH1A1MAPK1ALOX15 | |
| SCHEMBL3894118 | 0.81 | CYP3A4 (0.45) | CYP3A4TSHRALDH1A1MAPK1ALOX15 | |
| SCHEMBL5847207 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10CA12CA1 | |
| SCHEMBL5846633 | 0.79 | CA12 (0.37) | ALDH1A1HPGDHSD17B10CA12CA1 | |
| SCHEMBL13516413 | 0.79 | ALDH1A1 (0.41) | CYP3A4ALDH1A1CA1CA2CA9 | |
| SCHEMBL9772291 | 0.79 | TSHR (0.46) | CYP3A4TSHRALDH1A1MAPK1ALOX15 | |
| SCHEMBL6691030 | 0.79 | TSHR (0.46) | CYP3A4TSHRALDH1A1MAPK1ALOX15 | |
| SCHEMBL31053156 | 0.78 | CYP3A4 (0.50) | CYP3A4TSHRALDH1A1MAPK1ALOX15 | |
| SCHEMBL119351 | 0.78 | CYP3A4 (0.50) | CYP3A4TSHRALDH1A1MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041852-B2 | Perfluoroalkylanilines | BAYER CHEMICALS AG (DE) | 2006-05-09 | — | — | US | claimed |
| US-20040152898-A1 | Perfluoroalkylanilines | LANXESS DEUTSCHLAND GMBH (DE) | 2004-08-05 | — | — | US | claimed |
| EP-1418171-A1 | Perfluoroalkylanilins | Bayer Chemicals AG (DE) | 2004-05-12 | — | — | EP | claimed |
| EP-1418171-B1 | Verfahren zur Herstellung von Perfluoroalkylanilins | SALTIGO GMBH (DE) | 2011-12-14 | — | — | EP | disclosed |
| US-7041852-B2 | Perfluoroalkylanilines | BAYER CHEMICALS AG (DE) | 2006-05-09 | — | — | US | disclosed |
| US-20040152898-A1 | Perfluoroalkylanilines | LANXESS DEUTSCHLAND GMBH (DE) | 2004-08-05 | — | — | US | disclosed |
| EP-1418171-A1 | Perfluoroalkylanilins | Bayer Chemicals AG (DE) | 2004-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152898-A1 | Perfluoroalkylanilines | PFAS, AFF2, AFF4 | CYP3A4 97/4885TSHR 601/4885ALDH1A1 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.