SCHEMBL5847207

SCHEMBL5847207

Nc1ccc(C(F)(C(F)(F)F)C(F)(F)Br)cc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
KIF11 P52732 2/20 0.33
MPL P40238 1/20 0.32
IDO1 P14902 1/20 0.32
PKM P14618 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
KDM4E B2RXH2 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5366083 0.90 ALDH1A1 (0.48) ALDH1A1CA12CA1CA2CA4
SCHEMBL3894118 0.82 CYP3A4 (0.45) ALDH1A1PKMSMN1; SMN2KDM4E
SCHEMBL5846633 0.81 CA12 (0.37) ALDH1A1CA12CA1CA2CA4
SCHEMBL5845870 0.79 CYP3A4 (0.42) ALDH1A1CA12CA1CA2CA4
SCHEMBL18726208 0.79 FFAR4 (0.38) ALDH1A1KIF11PKMSMN1; SMN2KDM4E
SCHEMBL941310 0.78 ALDH1A1 (0.48) ALDH1A1CA12CA1CA2CA4
SCHEMBL9727879 0.78 ALDH1A1 (0.48) ALDH1A1CA12CA1CA2CA4
SCHEMBL379155 0.77 ALDH1A1 (0.52) ALDH1A1CA12CA1CA2CA4
SCHEMBL13516420 0.77
Hydrochloric Acid SCHEMBL30779699 0.75 IDO1 (0.52) ALDH1A1CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7041852-B2 Perfluoroalkylanilines BAYER CHEMICALS AG (DE) 2006-05-09 US claimed
US-20040152898-A1 Perfluoroalkylanilines LANXESS DEUTSCHLAND GMBH (DE) 2004-08-05 US claimed
EP-1418171-A1 Perfluoroalkylanilins Bayer Chemicals AG (DE) 2004-05-12 EP claimed
EP-1418171-B1 Verfahren zur Herstellung von Perfluoroalkylanilins SALTIGO GMBH (DE) 2011-12-14 EP disclosed
US-7041852-B2 Perfluoroalkylanilines BAYER CHEMICALS AG (DE) 2006-05-09 US disclosed
US-20040152898-A1 Perfluoroalkylanilines LANXESS DEUTSCHLAND GMBH (DE) 2004-08-05 US disclosed
EP-1418171-A1 Perfluoroalkylanilins Bayer Chemicals AG (DE) 2004-05-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152898-A1 Perfluoroalkylanilines PFAS, AFF2, AFF4 ALDH1A1 1098/4885CA12 4612/4885CA1 4510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.