Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359421 | 0.91 | DNM1 (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7909313 | 0.91 | DNM1 (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL23776320 | 0.86 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9311829 | 0.86 | TP53 (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10359458 | 0.86 | TP53 (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7901291 | 0.84 | DNM1 (0.47) | TSHRALDH1A1TP53CYP3A4HPGD | |
| SCHEMBL5845493 | 0.82 | THRB (0.46) | TSHRALDH1A1TP53HPGDDNM1 | |
| SCHEMBL11121824 | 0.81 | CYP2C9 (0.44) | TSHRALDH1A1TP53CYP3A4HPGD | |
| SCHEMBL7979746 | 0.81 | THRB (0.49) | TSHRALDH1A1TP53CYP3A4HPGD | |
| SCHEMBL11123619 | 0.79 | TSHR (0.47) | TSHRALDH1A1TP53CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125942-B2 | Acrylic esters of 2-cyano-2, 4 pentenedioic acid | CLAST TRADING LTD (HK) | 2006-10-24 | — | — | US | disclosed |
| US-20040249099-A1 | Acrylic esters of 2-cyano-2, 4 pentenedioic acid | CHEMENCE, INC. | 2004-12-09 | — | — | US | disclosed |