Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL390767 | 0.82 | GPR119 (0.68) | GPR119CYP2C9KCNH2 | |
| Hydrochloric Acid SCHEMBL1244784 | 0.81 | GPR119 (0.67) | GPR119CYP2C9KCNH2 | |
| SCHEMBL391186 | 0.80 | GPR119 (0.64) | GPR119CYP2C9KCNH2 | |
| SCHEMBL1245728 | 0.78 | GPR119 (0.65) | GPR119CYP2C9KCNH2 | |
| SCHEMBL28776749 | 0.75 | GPR119 (0.48) | GPR119 | |
| SCHEMBL27769080 | 0.74 | GPR119 (0.66) | GPR119CYP2C9KCNH2 | |
| SCHEMBL288589 | 0.73 | GPR119 (0.80) | GPR119CYP2C9KCNH2 | |
| SCHEMBL1071062 | 0.72 | GPR119 (0.75) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389488 | 0.71 | GPR119 (0.70) | GPR119CYP2C9KCNH2 | |
| SCHEMBL12835587 | 0.71 | GPR119 (0.54) | GPR119CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132426-B2 | Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2006-11-07 | — | — | US | claimed |