Pyrrole

Pyrrole

SCHEMBL584725

Cc1ccc[nH]1.c1cc[nH]c1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FKBP5 Q13451 1/20 0.35
DAO P14920 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
AURKA O14965 1/20 0.31
AURKB Q96GD4 1/20 0.31
INCENP Q9NQS7 1/20 0.31
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAOA P21397 1/20 0.31
HMBS P08397 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrole SCHEMBL27763221 0.97 FKBP5 (0.33) FKBP5DAOHDAC8HDAC6AURKA
SCHEMBL47202 0.89
Phosphine SCHEMBL27520992 0.86
SCHEMBL28875380 0.86
SCHEMBL27763245 0.86
SCHEMBL29278232 0.86
Bromide SCHEMBL15820960 0.86
Hydrogen Sulfide SCHEMBL29094906 0.86
SCHEMBL27869458 0.86
Ammonia Solution, Strong SCHEMBL27712725 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111187271-B Porphyrin organic small molecule receptor material, preparation method thereof and application thereof in organic solar cell 华南理工大学 2021-05-14 CN claimed
CN-111187271-A Porphyrin organic small molecule receptor material, preparation method thereof and application thereof in organic solar cell 华南理工大学 2020-05-22 CN claimed
US-20080281091-A1 Process for the Preparation of Porphyrin Derivatives as Antimicrobial Agents by Photodynamic Therapy (Pdt) BRUNDISH DEREK 2008-11-13 US claimed
EP-1963333-A1 PROCESS FOR THE PREPARATION OF PORPHYRIN DERIVATIVES AS ANTIMICROBIAL AGENTS BY PHOTODYNAMIC THERAPY (PDT) Destiny Pharma Limited (GB) 2008-09-03 EP claimed
WO-2007074340-A1 PROCESS FOR THE PREPARATION OF PORPHYRIN DERIVATIVES AS ANTIMICROBIAL AGENTS BY PHOTODYNAMIC THERAPY (PDT) DESTINY PHARMA LIMITED (GB) 2007-07-05 WO claimed
US-20050020560-A1 Chlorins processing fused ring systems useful as photoselective compounds for photodynamic therapy MIRAVANT PHARMACEUTICALS, INC. 2005-01-27 US claimed
WO-2001074818-A1 CHLORINS WITH FUSED RINGS FOR USE IN PHOTODYNAMIC THERAPY MIRAVANT PHARMACEUTICALS, INC. (US) 2001-10-11 WO claimed
US-5876864-A Fluorene-based alternating polymers containing acetylene group and electroluminescence element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 1999-03-02 US claimed
WO-2024119026-A1 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME NITTO DENKO CORPORATION (JP) 2024-06-06 WO disclosed
WO-2023158977-A1 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME NITTO DENKO CORPORATION (JP) 2023-08-24 WO disclosed
WO-2023158976-A1 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME NITTO DENKO CORPORATION (JP) 2023-08-24 WO disclosed
WO-2022178427-A9 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME NITTO DENKO CORPORATION (JP) 2023-07-27 WO disclosed
US-20230051807-A1 PORPHYRIN PHOTOSENSITIZER AND COBALOXIME COCATALYST AND METHODS OF USE THEREOF THE HONG KONG POLYTECHNIC UNIVERSITY (CN) 2023-02-16 US disclosed
WO-2022178427-A1 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME NITTO DENKO CORPORATION (JP) 2022-08-25 WO disclosed
WO-2003016330-A2 MOLECULAR LINKERS SUITABLE FOR CRYSTALLIZATION AND STRUCTURAL ANALYSIS OF MOLECULES OF INTEREST, METHOD OF USING SAME, AND METHODS OF PURIFYING G PROTEIN-COUPLED RECEPTORS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2003-02-27 WO disclosed
WO-2000053580-A2 N-PROTECTED SYNTHESIS METHOD FOR USE IN MAKING PORPHYRINS EMORY UNIVERSITY (US) 2000-09-14 WO disclosed
US-5876864-A Fluorene-based alternating polymers containing acetylene group and electroluminescence element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 1999-03-02 US disclosed
US-5807974-A POLYARYLENEVINYLENE RESIN KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-09-15 US disclosed
US-5750816-A USING CHROMIUM-BASED CATALYST SYSTEM COMPRISING A CHROMIUM COMPOUND, A NITROGEN-CONTAINING COMPOUND, AND AN ALKYLALUMINUM COMPOUND MITSUBISHI CHEMICAL CORPORATION (JP) 1998-05-12 US disclosed
US-4977117-A Reacting oxides of nickel and molybdenum with a polysulfide, in first stage without hydrogen and in second stage without hydrogen; arcylamine present EUROPEENNE DE RETRAITEMENT DE CATALYSEURS (FR) 1990-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230051807-A1 PORPHYRIN PHOTOSENSITIZER AND COBALOXIME COCATALYST AND METHODS OF USE THEREOF PPOX, HMBS, PNPO FKBP5 185/4885DAO 598/4885HDAC8 3525/4885
US-20050020560-A1 Chlorins processing fused ring systems useful as photoselective compounds for photodynamic therapy PPOX, HMBS, DDT FKBP5 1959/4885DAO 572/4885HDAC8 4563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.