Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5994671 | 0.75 | STAT3 (0.38) | ALDH1A1 | |
| SCHEMBL7755640 | 0.70 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL11822677 | 0.70 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL11829139 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL17882826 | 0.68 | SMN1; SMN2 (0.44) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL27508979 | 0.68 | ACMSD (0.46) | ALDH1A1MAPTACMSDPDE4BSMN1; SMN2 | |
| SCHEMBL5666289 | 0.67 | NAAA (0.47) | ALDH1A1GAATDP1 | |
| SCHEMBL5847226 | 0.67 | BACE1 (0.39) | ACMSDNOS3NOS1NOS2 | |
| SCHEMBL13956735 | 0.67 | POLB (0.51) | ALDH1A1MAPTLMNAHTTTDP1 | |
| SCHEMBL19212417 | 0.66 | BACE1 (0.38) | ALDH1A1KDM4EACMSDNOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094807-B2 | Substituted aryl thioureas and related compounds; inhibitors of viral replication | ACHILLION PHARMACEUTICALS, INC. (US) | 2006-08-22 | — | — | US | disclosed |