Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846604 | 0.87 | KDM4E (0.38) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL29573891 | 0.87 | KDM4E (0.38) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL19164650 | 0.85 | S100A4 (0.37) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL1808660 | 0.80 | KDM4E (0.41) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL22336460 | 0.80 | KDM4E (0.41) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL13523410 | 0.80 | KDM4E (0.41) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL6830565 | 0.78 | MEN1 (0.42) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL808025 | 0.78 | PDK2 (0.49) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL15138225 | 0.78 | PDK2 (0.49) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL19091592 | 0.74 | PDK2 (0.49) | PDK2KDM4EMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7088757-B1 | Use of spiro compounds as laser dyes | SEMICONDUCTORS GMBH (DE) | 2006-08-08 | — | — | US | disclosed |
| EP-1053578-B1 | USE OF SPIRO COMPOUNDS AS LASER DYES | COVION ORGANIC SEMICONDUCTORS (DE) | 2002-05-08 | — | — | EP | disclosed |