Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29573891 | 1.00 | KDM4E (0.38) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL19164650 | 0.98 | S100A4 (0.37) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL6830565 | 0.89 | MEN1 (0.42) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL5847445 | 0.87 | PDK2 (0.32) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL30231892 | 0.81 | KDM4E (0.42) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL15213650 | 0.81 | KDM4E (0.42) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL1982886 | 0.81 | PDK2 (0.33) | MEN1KMT2APDK2S100A4CYP1A2 | |
| SCHEMBL19530895 | 0.79 | MEN1 (0.41) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL26808385 | 0.79 | ALDH1A1 (0.43) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL16810779 | 0.78 | PDK2 (0.40) | KDM4EMEN1LMNAMAPTOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7088757-B1 | Use of spiro compounds as laser dyes | SEMICONDUCTORS GMBH (DE) | 2006-08-08 | — | — | US | disclosed |
| EP-1053578-B1 | USE OF SPIRO COMPOUNDS AS LASER DYES | COVION ORGANIC SEMICONDUCTORS (DE) | 2002-05-08 | — | — | EP | disclosed |
| EP-1053578-A1 | USE OF SPIRO COMPOUNDS AS LASER DYES | Axiva GmbH (DE) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040655-A1 | USE OF SPIRO COMPOUNDS AS LASER DYES | AXIVA GMBH (DE) | 1999-08-12 | — | — | WO | disclosed |