Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 11/20 | 0.56 |
| ▸ | DRD3 | P35462 | 5/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | DRD1 | P21728 | 3/20 | 0.56 |
| ▸ | DRD5 | P21918 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | HTR7 | P34969 | 3/20 | 0.56 |
| ▸ | HRH1 | P35367 | 3/20 | 0.56 |
| ▸ | HTR2B | P41595 | 3/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | CCR1 | P32246 | 3/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847484 | 0.88 | DRD2 (0.56) | DRD2DRD3HTR1ADRD1DRD5 | |
| SCHEMBL5848812 | 0.79 | CCR3 (0.59) | CCR3DRD2DRD3HTR1ADRD1 | |
| SCHEMBL14307260 | 0.78 | CCR3 (0.69) | CCR3DRD2DRD3HTR1ADRD1 | |
| SCHEMBL1132636 | 0.76 | CCR1 (0.65) | CCR3DRD2DRD3HTR1ADRD1 | |
| SCHEMBL11938907 | 0.76 | DRD2 (0.65) | CCR3DRD2DRD3HTR1ADRD1 | |
| SCHEMBL10610496 | 0.76 | DRD2 (0.65) | CCR3DRD2DRD3HTR1ADRD1 | |
| SCHEMBL10287607 | 0.74 | OPRM1 (0.63) | CCR3DRD2DRD3HTR1ADRD1 | |
| SCHEMBL5846508 | 0.74 | CCR3 (0.56) | CCR3DRD2DRD3HTR1ADRD1 | |
| SCHEMBL7402253 | 0.73 | CCR3 (1.00) | CCR3DRD2DRD3HTR1ADRD1 | |
| SCHEMBL11932477 | 0.73 | CCR1 (0.69) | CCR3DRD2DRD3ADRA1ACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39113-E1 | Utilization of derivatives of tetrahydropyridines(or 4-hydroxypiperidines)-butylazols in the preparation of a medicament for the treatment of pain | LABORATORIES DEL DR. ESTEVE, S.A. (ES) | 2006-05-30 | — | — | US | claimed |
| EP-1097698-B1 | UTILIZATION OF DERIVATIVES OF TETRAHYDROPYRIDINES (OR 4-HYDROXYPIPERIDINES)-BUTYLAZOLS IN THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF PAIN | ESTEVE LABOR DR (ES) | 2003-05-07 | — | — | EP | claimed |
| US-6384055-B1 | ANALGESICS | LABORATORIOS DEL DR. ESTEVES, S.A. (ES) | 2002-05-07 | — | — | US | claimed |
| EP-1097698-A2 | UTILIZATION OF DERIVATIVES OF TETRAHYDROPYRIDINES (OR 4-HYDROXYPIPERIDINES)-BUTYLAZOLS IN THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF PAIN | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2001-05-09 | — | — | EP | claimed |