⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706065 | 0.82 | — | — | |
| SCHEMBL689143 | 0.73 | — | — | |
| SCHEMBL228965 | 0.73 | — | — | |
| SCHEMBL34263 | 0.73 | — | — | |
| SCHEMBL1582020 | 0.73 | — | — | |
| Bromide SCHEMBL7801129 | 0.71 | — | — | |
| SCHEMBL11422024 | 0.71 | — | — | |
| SCHEMBL1502219 | 0.71 | — | — | |
| SCHEMBL15287134 | 0.70 | — | — | |
| SCHEMBL2764239 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143873-A | A kind of method of the intermediate 4- acetyl bromide methyl acetate of micro- reaction synthesis Method of cefcapene pivoxil side-chain acid | 济南大学 | 2019-08-20 | — | — | CN | claimed |
| CN-103351322-B | A kind of synthetic method of oxiracetam | GUANG'AN KINGDAY PHARM & CHEMICAL CO., LTD. (CN) | 2015-11-25 | — | — | CN | claimed |
| CN-103351322-A | Synthetic method of oxiracetam | GUANG AN KINGDAY PHARM & CHEMICAL CO LTD | 2013-10-16 | — | — | CN | claimed |
| EP-0156655-B1 | PROCESS FOR THE PREPARATION OF PYRROLIDONE DERIVATIVES | I.S.F. Socièta per Azioni (IT) | 1988-11-23 | — | — | EP | claimed |
| US-4629797-A | Process for the preparation of pyrrolidone derivatives | I.S.F. SOCIETA PER AZIONI (IT) | 1986-12-16 | — | — | US | claimed |
| EP-0156655-A2 | Process for the preparation of pyrrolidone derivatives | I.S.F. Socièta per Azioni (IT) | 1985-10-02 | — | — | EP | claimed |
| CN-110143873-A | A kind of method of the intermediate 4- acetyl bromide methyl acetate of micro- reaction synthesis Method of cefcapene pivoxil side-chain acid | 济南大学 | 2019-08-20 | — | — | CN | disclosed |
| CN-110143873-A | A kind of method of the intermediate 4- acetyl bromide methyl acetate of micro- reaction synthesis Method of cefcapene pivoxil side-chain acid | 济南大学 | 2019-08-20 | — | — | CN | disclosed |
| CN-106336418-B | A kind of solid-phase synthesis of cefotaxime hydrochloride | 上海上药新亚药业有限公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-103351322-B | A kind of synthetic method of oxiracetam | GUANG'AN KINGDAY PHARM & CHEMICAL CO., LTD. (CN) | 2015-11-25 | — | — | CN | disclosed |
| CN-102617506-B | Preparation method of cefdinir and its intermediate | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY SHIJIAZHUAN | 2015-04-01 | — | — | CN | disclosed |
| CN-102659817-B | Preparation method of cefdinir | ZHEJIANG POLUO DEBANG PHARMACEUTICAL CO LTD | 2014-07-02 | — | — | CN | disclosed |
| EP-2665731-A1 | FUSED AMINODIHYDROTHIAZINE DERIVATIVES | Eisai R&D Management Co., Ltd. (JP) | 2013-11-27 | — | — | EP | disclosed |
| EP-0006011-A1 | Cephalosporins and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1979-12-12 | — | — | EP | disclosed |
| US-4152433-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-05-01 | — | — | US | disclosed |
| US-4082807-A | REACTING AN AROMATIC COMPOUND WITH AN ACETOACETYL FLUORIDE; HYDROGEN FLUORIDE | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-04 | — | — | US | disclosed |
| US-4008246-A | Aminothiazole derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-02-15 | — | — | US | disclosed |
| US-3965168-A | CITRIC ACID INTERMEDIATE | ETHYL CORPORATION (US) | 1976-06-22 | — | — | US | disclosed |
| US-3960941-A | CHEMICAL INTERMEDIATE FOR CITRIC ACID | ETHYL CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |
| US-3937737-A | CHEMICAL INTERMEDIATES, DYES, PLASTICS, METAL COMPLEXES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-10 | — | — | US | disclosed |