Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2487068 | 0.81 | ATM (0.49) | ATMKDM4EL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL719767 | 0.81 | ATM (0.53) | MAPK1ATMKDM4EL3MBTL1PSMD14 | |
| SCHEMBL29833413 | 0.81 | ATM (0.49) | ATMKDM4EL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL8548159 | 0.81 | ALDH1A1 (0.43) | MAPK1ATMKDM4ENPSR1ALDH1A1 | |
| SCHEMBL3655489 | 0.80 | MAPK1 (0.47) | MAPK1ATMKDM4EL3MBTL1PSMD14 | |
| SCHEMBL8883732 | 0.80 | MAPT (0.47) | MAPK1ATMKDM4EL3MBTL1PSMD14 | |
| SCHEMBL27818191 | 0.80 | KDM4E (0.50) | MAPK1ATMKDM4EL3MBTL1PSMD14 | |
| SCHEMBL3520084 | 0.80 | MAPK1 (0.47) | MAPK1ATMKDM4EL3MBTL1PSMD14 | |
| SCHEMBL14260604 | 0.80 | OPRK1 (0.47) | KDM4EL3MBTL1NPSR1ALDH1A1GAA | |
| SCHEMBL29517846 | 0.80 | OPRK1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009058-B1 | Method for preparing pyridine-2,3-dicarboxylic acid esters | LONZA AG (CH) | 2006-03-07 | — | — | US | disclosed |
| US-4968803-A | FLUORINE AS OXIDANT | ALLIED-SIGNAL INC. (US) | 1990-11-06 | — | — | US | disclosed |