Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484382 | 0.85 | LMNA (0.45) | ALDH1A1SMN1; SMN2MAPTCYP1A2HPGD | |
| SCHEMBL22889973 | 0.83 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTCYP1A2HPGD | |
| SCHEMBL26101402 | 0.83 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2MAPTCYP1A2HPGD | |
| SCHEMBL31460215 | 0.82 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2MAPTCYP1A2HPGD | |
| SCHEMBL15635234 | 0.82 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2MAPTCYP1A2HPGD | |
| SCHEMBL5847766 | 0.81 | MAPK1 (0.49) | ALDH1A1MAPTHPGDNPSR1ATM | |
| SCHEMBL7576273 | 0.78 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2MAPTCYP1A2HPGD | |
| SCHEMBL31436355 | 0.78 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2MAPTCYP1A2HPGD | |
| SCHEMBL29833413 | 0.77 | ATM (0.49) | ALDH1A1SMN1; SMN2MAPTNPSR1ATM | |
| SCHEMBL2487068 | 0.77 | ATM (0.49) | ALDH1A1SMN1; SMN2MAPTNPSR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434965-B1 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID CO (US) | 1998-05-20 | — | — | EP | disclosed |
| US-5405827-A | 5-heterocyclic 2-(2-imidazolin-2-yl)pyridines, useful as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1995-04-11 | — | — | US | disclosed |
| US-5344935-A | Intermediates for herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| US-5283230-A | Pre- and post-emergence herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-02-01 | — | — | US | disclosed |
| US-5239070-A | Herbicide intermediates | AMERICAN CYANAMID COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| US-5225564-A | Acetalization, amination or sulfiding in a solvent | AMERICAN CYANAMID COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-5039333-A | 5-heterocyclic 2-(2-imidazolin-2-yl)pyridines, useful as herbicidal agents | AMERICAN CYANAMID COMPANY | 1991-08-13 | — | — | US | disclosed |
| EP-0434965-A2 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5026859-A | Intermediates for herbicides | AMERICAN CYANAMID COMPANY (US) | 1991-06-25 | — | — | US | disclosed |