SCHEMBL584803

SCHEMBL584803

Cc1coc(Cc2ccccc2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 3/20 0.54
CALM1 P0DP23 1/20 0.42
DAO P14920 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 2/20 0.36
BCL2 P10415 1/20 0.36
BCL2L1 Q07817 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAPT P10636 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TSHR P16473 1/20 0.36
CYP11B1 P15538 2/20 0.36
CYP11B2 P19099 2/20 0.36
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25128526 0.80 MAOB (0.42) IDH1ALDH1A1NPC1RAB9ACYP11B1
SCHEMBL27719076 0.79 IDH1 (0.58) IDH1CALM1DAOSMN1; SMN2ALDH1A1
SCHEMBL11483794 0.78 IDH1 (0.57) IDH1CALM1DAOALDH1A1BCL2
SCHEMBL15978541 0.78 IDH1 (0.53) IDH1CALM1DAOALDH1A1BCL2
SCHEMBL13474923 0.78 DAO (0.59) DAOL3MBTL1MAPTTSHR
SCHEMBL14769145 0.78 IDH1 (0.66) IDH1DAOALDH1A1CYP11B1CYP11B2
SCHEMBL584802 0.76 IDH1 (0.54) IDH1CALM1DAOSMN1; SMN2ALDH1A1
SCHEMBL11040268 0.76 IDH1 (0.64) IDH1CALM1DAOBCL2BCL2L1
SCHEMBL11125823 0.76 IDH1 (0.54) IDH1CALM1DAOSMN1; SMN2ALDH1A1
SCHEMBL21153740 0.76 IDH1 (0.50) IDH1CALM1DAOSMN1; SMN2BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1085 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325385-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2017-10-04 EP claimed
EP-1729574-B1 PESTICIDE COMPOSITIONS DOW AGROSCIENCES LLC (US) 2015-01-07 EP claimed
CN-102396509-A High-efficiency mothproofing agent product SURYAMAS DAILY CHEMICAL TIANJIN CO LTD 2012-04-04 CN claimed
EP-1697578-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2011-08-31 EP claimed
EP-2325385-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF SE (DE) 2011-05-25 EP claimed
US-20110002877-A1 PTEN Inhibitors Treat Neutropenia-Associated Pneumonia CHILDREN'S MEDICAL CENTER CORPORATION 2011-01-06 US claimed
US-7793920-B2 barrier against insect; the net structure made of polymer fibers is impregnated with an insecticide; preventing the low flying insects from entering open-air area; black color; invisible to certain insects VESTERGAARD SA (CH) 2010-09-14 US claimed
CN-100508745-C A fencing VESTERGAARD CO LTD (DK) 2009-07-08 CN claimed
US-20070292464-A1 FIBERS AND SHEET-FORM TEXTILES PROVIDED WITH INSECT-REPELLENT FINISHES FASHION CHEMICALS GMBH & CO. KG (DE) 2007-12-20 US claimed
EP-1845186-A1 Fibres and textile sheet prepared for repelling insects Cognis IP Management GmbH (DE) 2007-10-17 EP claimed
US-4225612-A Heterocyclic-substituted cyclopropanecarboxylate pesticides SHELL OIL COMPANY (US) 1980-09-30 US claimed
US-4224227-A PESTICIDES ROUSSEL UCLAF (FR) 1980-09-23 US claimed
US-4183942-A Insecticidal (β-phenyl-β-substituted-vinyl)cyclopropanecarboxylates FMC CORPORATION (US) 1980-01-15 US claimed
EP-0005882-A1 A method of combating acarine pests by means of oxyimino-substituted cyclopropane-carboxylate esters, Z-isomers of certain such esters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1979-12-12 EP claimed
US-4166064-A 4,6,6,6 -TETRACHLORO-3,3-DIMETHYLHEXANOATE, ALKALI METAL TERT-ALKOXIDE FMC CORPORATION (US) 1979-08-28 US claimed
EP-0003683-A2 Process for preparing high cis 3-(2,2,2-trichloroethyl)-2,2-dimethylcyclopropane-1-carboxylates FMC Corporation (US) 1979-08-22 EP claimed
EP-0003336-A2 Insecticidal perhaloalkylvinylcyclopropanecarboxylates FMC Corporation (US) 1979-08-08 EP claimed
US-4160842-A Insecticidal [β-(substituted-phenyl)vinyl]cyclopropanecarboxylates FMC CORPORATION (US) 1979-07-10 US claimed
US-4157397-A RESISTANT TO PHOTOOXIDATIVE DEGRADATION FMC CORPORATION (US) 1979-06-05 US claimed
US-4000266-A (1-CYCLOHEXENE-1,2-DICARBOXAMIDO)METHYL CHRYSANTHEMUMATE, (5-BENZYL-3-FURYL)METHYL CHRYSANTHEMUMATE FMC CORPORATION (US) 1976-12-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110002877-A1 PTEN Inhibitors Treat Neutropenia-Associated Pneumonia CSF3R, CSF1R, ATM IDH1 964/4885CALM1 4330/4885DAO 4125/4885
US-20070292464-A1 FIBERS AND SHEET-FORM TEXTILES PROVIDED WITH INSECT-REPELLENT FINISHES CUTA, DBF4, MFAP1 IDH1 4844/4885CALM1 3690/4885DAO 3851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.