Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 8/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | EBP | Q15125 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847140 | 0.76 | OPRL1 (0.56) | OPRL1OPRM1OPRD1ABCB11TP53 | |
| SCHEMBL14117480 | 0.75 | OPRL1 (0.74) | OPRL1OPRM1OPRD1ABCB11TP53 | |
| SCHEMBL5848902 | 0.74 | OPRL1 (0.54) | OPRL1OPRM1OPRD1ABCB11TP53 | |
| SCHEMBL18029400 | 0.73 | OPRL1 (0.70) | OPRL1OPRM1OPRD1ABCB11TP53 | |
| SCHEMBL7104650 | 0.73 | OPRL1 (0.65) | OPRL1OPRM1OPRD1ABCB11TP53 | |
| SCHEMBL3136902 | 0.72 | OPRL1 (0.86) | OPRL1OPRM1OPRD1SMN1; SMN2OPRK1 | |
| SCHEMBL9053345 | 0.72 | ABCB11 (0.85) | OPRL1OPRM1OPRD1ABCB11TP53 | |
| SCHEMBL11837987 | 0.72 | ABCB11 (0.68) | OPRL1OPRM1OPRD1ABCB11TP53 | |
| Hydrochloric Acid SCHEMBL4813917 | 0.72 | OPRL1 (0.84) | OPRL1OPRM1OPRD1KDM4EPMP22 | |
| SCHEMBL11792849 | 0.71 | SIGMAR1 (0.67) | OPRL1OPRM1OPRD1ABCB11TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39113-E1 | Utilization of derivatives of tetrahydropyridines(or 4-hydroxypiperidines)-butylazols in the preparation of a medicament for the treatment of pain | LABORATORIES DEL DR. ESTEVE, S.A. (ES) | 2006-05-30 | — | — | US | claimed |
| US-6384055-B1 | ANALGESICS | LABORATORIOS DEL DR. ESTEVES, S.A. (ES) | 2002-05-07 | — | — | US | claimed |