SCHEMBL5848385

SCHEMBL5848385

Fc1ccc(OC=S)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 2/20 0.41
MAOB P27338 4/20 0.35
MAOA P21397 2/20 0.35
SOS1 Q07889 1/20 0.34
HSPB1 P04792 1/20 0.34
AOC2 O75106 1/20 0.34
DAO P14920 1/20 0.34
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NQO2 P16083 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
LMNA P02545 1/20 0.33
APP P05067 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2980634 0.93 NFE2L2 (0.38) NFE2L2MAOBMAOASOS1HSPB1
SCHEMBL7867836 0.74 IDO1 (0.33)
SCHEMBL5828142 0.74
SCHEMBL95870 0.74 NFE2L2 (0.41) NFE2L2MAOBMAOASOS1HSPB1
SCHEMBL1259185 0.74 NFE2L2 (0.46) NFE2L2MAOBMAOASOS1HSPB1
SCHEMBL13665332 0.74 SOS1 (0.43) NFE2L2MAOBMAOASOS1HSPB1
SCHEMBL8495621 0.74 ACHE (0.48) ALDH1A1L3MBTL1CA1CA2CA7
SCHEMBL410307 0.74 NFE2L2 (0.41) NFE2L2MAOBMAOASOS1HSPB1
SCHEMBL6570976 0.74 CYP2A6 (0.42) MAOBMAOAALDH1A1L3MBTL1CA1
SCHEMBL2494427 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7138538-B2 Process for the separation of enantiomers and enantiopure reagent SOLVAY (SOCIETE ANONYME) (BE) 2006-11-21 US claimed
US-20040210060-A1 Process for the separation of enantiomers and enantiopure reagent SOLVAY S.A. (BE) 2004-10-21 US claimed
CN-117903022-A Application of zirconium hydroxide as catalyst in preparing sulfoxide and sulfone by selective catalytic oxidation of thioether 兰州大学 2024-04-19 CN disclosed
US-7138538-B2 Process for the separation of enantiomers and enantiopure reagent SOLVAY (SOCIETE ANONYME) (BE) 2006-11-21 US disclosed
US-20040210060-A1 Process for the separation of enantiomers and enantiopure reagent SOLVAY S.A. (BE) 2004-10-21 US disclosed
EP-1046627-B1 Enantiopure reagents and process for the separation of enantiomers SOLVAY (BE) 2004-02-11 EP disclosed
EP-1046627-A2 Enantiopure reagents and process for the separation of enantiomers SOLVAY (Société Anonyme) (BE) 2000-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040210060-A1 Process for the separation of enantiomers and enantiopure reagent DNPEP, DAO, ANPEP NFE2L2 1858/4885MAOB 168/4885MAOA 244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.