SCHEMBL410307

SCHEMBL410307

C=COc1ccc(F)cc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.41
SOS1 Q07889 1/20 0.34
HSPB1 P04792 1/20 0.34
TGM2 P21980 1/20 0.34
MAOB P27338 5/20 0.34
AOC2 O75106 1/20 0.34
DAO P14920 1/20 0.34
MAOA P21397 1/20 0.34
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NQO2 P16083 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
LMNA P02545 1/20 0.33
APP P05067 1/20 0.33
ACHE P22303 1/20 0.33
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19835684 0.93 NFE2L2 (0.38) NFE2L2SOS1HSPB1TGM2MAOB
SCHEMBL473606 0.86 CHRNB2 (0.34) ALDH1A1CA1CA2CA7CA9
SCHEMBL14289128 0.78 ALDH1A1 (0.44) TGM2MAOBMAOAALDH1A1LMNA
SCHEMBL11965976 0.78 ESR2 (0.33) ALDH1A1LMNA
SCHEMBL24636596 0.74 CHRNB2 (0.30)
SCHEMBL14605389 0.74 IDO1 (0.33)
SCHEMBL194091 0.74 ACHE (0.48) TGM2ALDH1A1L3MBTL1CA1CA2
SCHEMBL126186 0.74 ALDH1A1 (0.58) ALDH1A1LMNA
SCHEMBL17186614 0.74 NPC1 (0.32) ALDH1A1LMNA
SCHEMBL1259185 0.74 NFE2L2 (0.46) NFE2L2SOS1HSPB1MAOBAOC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61120162-A None JP disclosed
EP-4722199-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2026-04-08 EP disclosed
US-20250109101-A1 NAPHTHALENE COMPOUND, SYNTHESIS METHOD THEREFOR, AND COMPOSITION CONTAINING SAID NAPHTHALENE COMPOUND SHIKOKU CHEMICALS CORPORATION (JP) 2025-04-03 US disclosed
WO-2024247919-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF 四国化成工業株式会社 2024-12-05 WO disclosed
EP-4464691-A2 NAPHTHALENE COMPOUND, SYNTHESIS METHOD THEREFOR, AND COMPOSITION CONTAINING SAID NAPHTHALENE COMPOUND Shikoku Chemicals Corporation (JP) 2024-11-20 EP disclosed
CN-118541350-A Naphthalene compound, method for synthesizing the same, and composition containing the same 四国化成工业株式会社 2024-08-23 CN disclosed
WO-2023058781-A2 NAPHTHALENE COMPOUND, SYNTHESIS METHOD THEREFOR, AND COMPOSITION CONTAINING SAID NAPHTHALENE COMPOUND 四国化成工業株式会社 2023-04-13 WO disclosed
US-10766973-B2 Method for producing polymer for electronic material and polymer for electronic material obtained by the production method MARUZEN PETROCHEMICAL CO., LTD. (JP) 2020-09-08 US disclosed
US-20190002604-A1 HETERORING-CONTAINING SILOXANE POLYMER, COMPOSITION CONTAINING SAID POLYMER, AND ELECTRONIC ELEMENT DAINIPPON INK & CHEMICALS (JP) 2019-01-03 US disclosed
US-20180223181-A1 SILOXANE MONOMER, POLYMER THEREOF, COMPOSITION CONTAINING SAID POLYMER, AND ELECTRONIC ELEMENT DAINIPPON INK & CHEMICALS (JP) 2018-08-09 US disclosed
EP-2186837-A1 ABA TRIBLOCK COPOLYMER AND PROCESS FOR PRODUCING THE SAME MARUZEN PETROCHEMICAL CO., LTD. (JP) 2010-05-19 EP disclosed
US-20080227977-A1 Thiol compound derivative, curable composition containing the derivative, and molded product thereof UNIMATEC CO., LTD. 2008-09-18 US disclosed
US-7384995-B2 Thiol compound derivative, curable composition containing the derivative, and molded product thereof UNIMATEC CO., LTD. (JP) 2008-06-10 US disclosed
US-20070155868-A1 Thiol compound derivative, curable composition containing the derivative, and molded product thereof UNIMATEC CO., LTD. 2007-07-05 US disclosed
US-7199169-B2 Thiol compound derivative, hardening compositions containing these derivatives and molded articles thereof UNIMATEC CO., LTD. (JP) 2007-04-03 US disclosed
US-20040162368-A1 Thiol compound derivative, hardening compositions containing these derivatives and molded articles thereof UNIMATEC CO., LTD. (JP) 2004-08-19 US disclosed
EP-1394153-A1 THIOL COMPOUND DERIVATIVES, HARDENING COMPOSITIONS CONTAINING THESE DERIVATIVES AND MOLDED ARTICLES THEREOF Unimatec Co., Ltd. (JP) 2004-03-03 EP disclosed
EP-0285936-B1 3,4-DIHYDRO-2H-PYRANS BASF Aktiengesellschaft (DE) 1990-05-30 EP disclosed
EP-0285936-A1 3,4-Dihydro-2H-pyrans BASF Aktiengesellschaft (DE) 1988-10-12 EP disclosed
JP-S61120162-A MICROENCAPSULATED TONER KONISHIROKU PHOTO IND CO LTD 1986-06-07 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180223181-A1 SILOXANE MONOMER, POLYMER THEREOF, COMPOSITION CONTAINING SAID POLYMER, AND ELECTRONIC ELEMENT ILK, LIMA1, EED NFE2L2 2002/4885SOS1 192/4885HSPB1 3009/4885
US-20080227977-A1 Thiol compound derivative, curable composition containing the derivative, and molded product thereof TST, CTH, NACA NFE2L2 2556/4885SOS1 2674/4885HSPB1 2191/4885
US-20040162368-A1 Thiol compound derivative, hardening compositions containing these derivatives and molded articles thereof TST, NACA, CTH NFE2L2 1533/4885SOS1 2918/4885HSPB1 1537/4885
US-20250109101-A1 NAPHTHALENE COMPOUND, SYNTHESIS METHOD THEREFOR, AND COMPOSITION CONTAINING SAID NAPHTHALENE COMPOUND C1S, CDH1, L1CAM NFE2L2 778/4885SOS1 428/4885HSPB1 2539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.