Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | GALR3 | O60755 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329740 | 0.91 | ADRB3 (0.53) | ADRB3ADRB1LMNAHIF1AGALR3 | |
| SCHEMBL12186418 | 0.87 | ADRB3 (0.57) | ADRB3ADRB1LMNAADRB2 | |
| SCHEMBL10876266 | 0.87 | LMNA (0.69) | ADRB3ADRB1LMNAHIF1AGALR3 | |
| SCHEMBL16552549 | 0.85 | SLC6A2 (0.43) | ADRB3ADRB1LMNAADRB2SLC2A1 | |
| SCHEMBL11748376 | 0.84 | ADRB3 (0.55) | ADRB3ADRB1LMNAADRB2 | |
| SCHEMBL8424936 | 0.84 | ADRB3 (0.55) | ADRB3ADRB1LMNAADRB2 | |
| SCHEMBL12186388 | 0.83 | ADRB3 (0.57) | ADRB3ADRB1LMNAHIF1AGALR3 | |
| SCHEMBL5848382 | 0.81 | HIF1A (0.53) | ADRB3ADRB1LMNAHIF1AGALR3 | |
| SCHEMBL5848447 | 0.81 | HIF1A (0.53) | ADRB3ADRB1LMNAHIF1AGALR3 | |
| SCHEMBL27562212 | 0.81 | LMNA (0.56) | ADRB3ADRB1LMNAHIF1AGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112605-B2 | Sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones, preparation method, and medical use thereof | Research Institute of Materia Medica Chinese Acadamy of Medical Sciences (CN) | 2006-09-26 | — | — | US | disclosed |
| US-20040029951-A1 | Sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones, preparation method, and medical use thereof | RESEARCH INSTITUTE OF MATERIAL MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES; | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029951-A1 | Sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones, preparation method, and medical use thereof | PTGS1, PTGS2, PTGER1 | ADRB3 587/4885ADRB1 881/4885LMNA 2751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.