SCHEMBL5849425

SCHEMBL5849425

ICCCCCCCCOC1CCCCO1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
KDM4C Q9H3R0 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31077517 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL31077652 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL31077655 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL19172278 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL9204036 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL5849818 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL4732986 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL5849811 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL2744123 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL5849446 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230256098-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2023-08-17 US disclosed
US-11679158-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2023-06-20 US disclosed
US-11633479-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2023-04-25 US disclosed
US-20220175928-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2022-06-09 US disclosed
US-10369226-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2019-08-06 US disclosed
US-9682922-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2017-06-20 US disclosed
EP-2575764-B1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS INC (US) 2017-04-19 EP disclosed
US-9012498-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2015-04-21 US disclosed
US-20120027803-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2012-02-02 US disclosed
US-7153844-B2 Estrogen-linked platinum (II) complexes as anticancer agents Berube, Gervais (CA) 2006-12-26 US disclosed
US-20040006051-A1 Estrogen-linked platinum (II) complexes as anticancer agents GERVAIS BERUBE (CA) 2004-01-08 US disclosed
EP-1179529-A1 NOVEL HYDROXAMIC ACID DERIVATIVES Daiichi Fine Chemical Co., Ltd. (JP) 2002-02-13 EP disclosed
EP-1038864-A1 NOVEL METALLOPROTEINASE INHIBITORS FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 2000-09-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120027803-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, CETP, APOB MEN1 2354/4885KMT2A 4134/4885KDM4C 4330/4885
US-11633479-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP MEN1 2092/4885KMT2A 4005/4885KDM4C 4358/4885
US-10369226-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP MEN1 2092/4885KMT2A 4005/4885KDM4C 4358/4885
US-20040006051-A1 Estrogen-linked platinum (II) complexes as anticancer agents ESR2, PGR, ESR1 MEN1 814/4885KMT2A 2911/4885KDM4C 2149/4885
US-20220175928-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP MEN1 2092/4885KMT2A 4005/4885KDM4C 4358/4885
US-11679158-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP MEN1 2092/4885KMT2A 4005/4885KDM4C 4358/4885
US-20230256098-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP MEN1 2092/4885KMT2A 4005/4885KDM4C 4358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.