SCHEMBL5849446

SCHEMBL5849446

ICCCCCCOC1CCCCO1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
KDM4C Q9H3R0 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31077517 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL31077652 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL31077655 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL19172278 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL9204036 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL5849818 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL4732986 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL5849811 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL5849425 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL2744123 1.00 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8022235-B2 Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use CELLECTAR, INC. (US) 2011-09-20 US disclosed
US-7893286-B2 Method for the synthesis of phospholipid ethers CELLECTAR, INC. (US) 2011-02-22 US disclosed
US-20090018357-A1 Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use CELL ACQUISITION CORP. 2009-01-15 US disclosed
US-20080312459-A1 Method for the synthesis of phospholipid ethers CELL ACQUISITION CORP. 2008-12-18 US disclosed
US-20070167524-A1 Capsaicin derivates and the production and use thereof AXICHEM AB (SE) 2007-07-19 US disclosed
US-20070014756-A1 Composition and method for treating the gastro-intestinal tract TOUCHOT NICHOLAS 2007-01-18 US disclosed
US-7153844-B2 Estrogen-linked platinum (II) complexes as anticancer agents Berube, Gervais (CA) 2006-12-26 US disclosed
US-20040006051-A1 Estrogen-linked platinum (II) complexes as anticancer agents GERVAIS BERUBE (CA) 2004-01-08 US disclosed
EP-0169033-B1 INHIBITORS OF SLOW REACTING SUBSTANCE OF ANAPHYLAXIS SCHERING CORPORATION (US) 1992-02-12 EP disclosed
EP-0169033-A2 Inhibitors of slow reacting substance of anaphylaxis SCHERING CORPORATION (US) 1986-01-22 EP disclosed
US-4089897-A Geminal prostaglandin analogs MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-05-16 US disclosed
US-4090019-A Geminal prostaglandin analogs MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070167524-A1 Capsaicin derivates and the production and use thereof TRPV1, TRPA1, TRPV2 MEN1 2441/4885KMT2A 1567/4885KDM4C 2432/4885
US-20040006051-A1 Estrogen-linked platinum (II) complexes as anticancer agents ESR2, PGR, ESR1 MEN1 814/4885KMT2A 2911/4885KDM4C 2149/4885
US-20070014756-A1 Composition and method for treating the gastro-intestinal tract GIPR, FABP2, FABP6 MEN1 4171/4885KMT2A 3349/4885KDM4C 4398/4885
US-20090018357-A1 Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use PHOSPHO1, PEBP1, SGMS1 MEN1 449/4885KMT2A 2096/4885KDM4C 1647/4885
US-20080312459-A1 Method for the synthesis of phospholipid ethers PHOSPHO1, PLEC, PLA2G2C MEN1 365/4885KMT2A 1176/4885KDM4C 996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.