SCHEMBL1246548

SCHEMBL1246548

O=C(NCCO)c1ccccc1C(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.53
HDAC3 O15379 1/20 0.52
HDAC1 Q13547 1/20 0.52
ALDH1A1 P00352 3/20 0.51
MAPT P10636 2/20 0.51
KDM4E B2RXH2 1/20 0.51
CASP1 P29466 1/20 0.51
CASP7 P55210 1/20 0.51
HTT P42858 3/20 0.51
TSHR P16473 1/20 0.50
MEN1 O00255 1/20 0.50
CACNA1B Q00975 1/20 0.50
APBA1 Q02410 1/20 0.50
KMT2A Q03164 1/20 0.50
POLB P06746 1/20 0.49
CAPN1 P07384 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
OPRL1 P41146 1/20 0.46
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7160309 0.90 HTT (0.63) AKR1C3HDAC3HDAC1ALDH1A1MAPT
SCHEMBL8894839 0.87 ALDH1A1 (0.62) ALDH1A1MAPTKDM4ECASP1CASP7
SCHEMBL1246757 0.85 HDAC3 (0.57) AKR1C3HDAC3HDAC1ALDH1A1MAPT
SCHEMBL5849754 0.84 HTT (0.63) ALDH1A1MAPTKDM4ECASP1CASP7
SCHEMBL9695573 0.84 HTT (0.63) ALDH1A1MAPTKDM4ECASP1CASP7
SCHEMBL16046339 0.83 ALDH1A1 (0.52) AKR1C3HDAC3HDAC1ALDH1A1MAPT
SCHEMBL1246967 0.82 LMNA (0.61) HDAC3HDAC1ALDH1A1HTTMEN1
SCHEMBL305562 0.81 GAA (0.65) HDAC3HDAC1HTTKMT2APOLB
Hydrochloric Acid SCHEMBL6421806 0.80 GAA (0.63) HDAC3HDAC1HTTKMT2APOLB
SCHEMBL9570919 0.79 ALDH1A1 (0.54) ALDH1A1MAPTKDM4ECASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10252291-B2 Photo-curing of thermoplastic coatings COLOPLAST A/S (DK) 2019-04-09 US disclosed
EP-2394676-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITIATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2018-03-28 EP disclosed
CN-103468108-B Coating composition COLOPLAST A/S (DK) 2016-03-02 CN disclosed
EP-2459242-B1 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST AS (DK) 2015-10-21 EP disclosed
EP-2104523-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2015-08-26 EP disclosed
US-8932662-B2 Coatings prepared from poly(ethylene oxide) and photo-initator-containing scaffolds COLOPLAST A/S (DK) 2015-01-13 US disclosed
EP-2049172-B1 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST AS (DK) 2014-12-31 EP disclosed
US-20140363562-A1 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST A/S (DK) 2014-12-11 US disclosed
CN-103131315-A Coating composition COLOPLAST AS 2013-06-05 CN disclosed
US-20130115466-A1 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST A/S (DK) 2013-05-09 US disclosed
EP-2459242-A2 A MEDICAL DEVICE OF POLYOLEFIN Coloplast A/S (DK) 2012-06-06 EP disclosed
US-20120121919-A1 MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2012-05-17 US disclosed
WO-2011012137-A2 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2011-02-03 WO disclosed
US-20100119833-A1 PHOTO-CURING OF THERMOPLASTIC COATINGS MADSEN NIELS JORGEN 2010-05-13 US disclosed
US-20100049146-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2010-02-25 US disclosed
EP-2104523-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS Coloplast A/S (DK) 2009-09-30 EP disclosed
EP-2049172-A2 PHOTO-CURING OF THERMOPLASTIC COATINGS Coloplast A/S (DK) 2009-04-22 EP disclosed
WO-2008071796-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2008-06-19 WO disclosed
WO-2008012325-A2 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST A/S (DK) 2008-01-31 WO disclosed