Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HSD17B1 | P14061 | 8/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | STS | P08842 | 4/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12379505 | 0.87 | USP2 (0.64) | MAPTUSP2MAPK1HSD17B1HRH3 | |
| SCHEMBL12418333 | 0.85 | HSD17B1 (0.63) | MAPTUSP2MAPK1HSD17B1HRH3 | |
| SCHEMBL12379510 | 0.83 | HSD17B1 (0.76) | MAPTUSP2MAPK1HSD17B1HRH3 | |
| SCHEMBL218225 | 0.83 | USP2 (0.55) | MAPTUSP2MAPK1HRH3STS | |
| SCHEMBL5849876 | 0.83 | MAPT (0.74) | MAPTUSP2MAPK1HSD17B1HRH3 | |
| SCHEMBL218306 | 0.83 | USP2 (0.55) | MAPTUSP2MAPK1HRH3STS | |
| SCHEMBL12379440 | 0.83 | MAPT (0.63) | MAPTUSP2MAPK1HSD17B1HRH3 | |
| SCHEMBL2292483 | 0.83 | MAPT (0.63) | MAPTUSP2MAPK1HSD17B1HRH3 | |
| SCHEMBL216338 | 0.82 | USP2 (0.56) | MAPTUSP2MAPK1HRH3STS | |
| SCHEMBL19705233 | 0.82 | USP2 (0.56) | MAPTUSP2MAPK1HRH3STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153844-B2 | Estrogen-linked platinum (II) complexes as anticancer agents | Berube, Gervais (CA) | 2006-12-26 | — | — | US | disclosed |
| US-20040006051-A1 | Estrogen-linked platinum (II) complexes as anticancer agents | GERVAIS BERUBE (CA) | 2004-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006051-A1 | Estrogen-linked platinum (II) complexes as anticancer agents | ESR2, PGR, ESR1 | MAPT 4639/4885USP2 2483/4885MAPK1 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.