SCHEMBL585003

SCHEMBL585003

CCCCOCCOCCOc1c(Br)sc(Br)c1OCCOCCOCCCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
CYP3A4 P08684 3/20 0.39
RARB P10826 4/20 0.38
THRB P10828 4/20 0.37
THRA P10827 3/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HTT P42858 1/20 0.36
MAPT P10636 1/20 0.36
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35
SLCO1B3 Q9NPD5 1/20 0.35
SLCO1B1 Q9Y6L6 1/20 0.35
RARA P10276 2/20 0.33
RARG P13631 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13669530 0.90 THRA (0.43) TSHRCYP3A4THRBTHRAMEN1
SCHEMBL13101332 0.89 TSHR (0.39) TSHRCYP3A4RARBTHRBTHRA
SCHEMBL583974 0.83 L3MBTL1 (0.35) TSHRRARBKMT2AMAPTALDH1A1
SCHEMBL30423452 0.82 THRB (0.46) TSHRTHRBTHRAMEN1KMT2A
SCHEMBL10013253 0.80 TSHR (0.44) TSHRCYP3A4RARBTHRBMEN1
SCHEMBL585156 0.79 MAPT (0.33) MAPTALDH1A1LMNA
SCHEMBL13084306 0.77 TSHR (0.38) TSHRCYP3A4RARBTHRBMEN1
SCHEMBL17903275 0.77 MEN1 (0.42) TSHRCYP3A4RARBTHRBMEN1
SCHEMBL19910831 0.77 NPC1 (0.39) MAPTALDH1A1SMN1; SMN2
SCHEMBL15258220 0.76 TSHR (0.40) TSHRCYP3A4RARBTHRBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9978473-B2 Doping methods for hole injection and transport layers NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-05-22 US disclosed
US-9397294-B2 Vertically phase-separating semiconducting organic material layers SOLVAY USA, INC. (US) 2016-07-19 US disclosed
US-9139688-B2 Copolymers of 3,4-dialkoxythiophenes and methods for making and devices SOLVAY USA, INC. (US) 2015-09-22 US disclosed
EP-2851383-A1 Doped conjugated polymers, devices, and methods of making devices Solvay USA Inc. (US) 2015-03-25 EP disclosed
US-20150028322-A1 DOPED CONJUGATED POLYMERS, DEVICES, AND METHODS OF MAKING DEVICES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-01-29 US disclosed
US-8865025-B2 Doped conjugated polymers, devices, and methods of making devices SOLVAY USA, INC. (US) 2014-10-21 US disclosed
EP-2276788-B1 DOPED CONJUGATED POLYMERS, DEVICES, AND METHODS OF MAKING DEVICES PLEXTRONICS INC (US) 2014-08-27 EP disclosed
EP-2764518-A1 IMPROVED DOPING METHODS FOR HOLE INJECTION AND TRANSPORT LAYERS Plextronics, Inc. (US) 2014-08-13 EP disclosed
US-20140217334-A1 DOPING CONJUGATED POLYMERS AND DEVICES PLEXTRONICS, INC. (US) 2014-08-07 US disclosed
EP-2729532-A1 VERTICALLY PHASE-SEPARATING SEMICONDUCTING ORGANIC MATERIAL LAYERS Plextronics, Inc. (US) 2014-05-14 EP disclosed
EP-2513187-A2 COPOLYMERS OF 3,4-DIALKOXYTHIOPHENES AND METHODS FOR MAKING AND DEVICES Plextronics, Inc. (US) 2012-10-24 EP disclosed
EP-2417178-A1 DEHALOGENATION Plextronics, Inc. (US) 2012-02-15 EP disclosed
US-20110278559-A1 DOPING CONJUGATED POLYMERS AND DEVICES PLEXTRONICS, INC. 2011-11-17 US disclosed
WO-2011143196-A1 DOPING CONJUGATED POLYMERS AND DEVICES PLEXTRONICS, INC. (US) 2011-11-17 WO disclosed
WO-2011075644-A2 COPOLYMERS OF 3,4-DIALKOXYTHIOPHENES AND METHODS FOR MAKING AND DEVICES PLEXTRONICS, INC. (US) 2011-06-23 WO disclosed
EP-2276788-A1 DOPED CONJUGATED POLYMERS, DEVICES, AND METHODS OF MAKING DEVICES Plextronics, Inc. (US) 2011-01-26 EP disclosed
US-20100273007-A1 DEHALOGENATION PLEXTRONICS, INC. 2010-10-28 US disclosed
WO-2010118370-A1 DEHALOGENATION PLEXTRONICS, INC. (US) 2010-10-14 WO disclosed
US-20090256117-A1 DOPED CONJUGATED POLYMERS, DEVICES, AND METHODS OF MAKING DEVICES PLEXTRONICS, INC. 2009-10-15 US disclosed
WO-2009126918-A1 DOPED CONJUGATED POLYMERS, DEVICES, AND METHODS OF MAKING DEVICES PLEXTRONICS, INC. (US) 2009-10-15 WO disclosed