Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855470 | 0.93 | HTR6 (0.42) | KMT2AHTR6SMN1; SMN2HTTMAPT | |
| SCHEMBL6850300 | 0.93 | SMN1; SMN2 (0.39) | KMT2AHTR6SMN1; SMN2HTTMAPT | |
| SCHEMBL5851079 | 0.93 | HTR6 (0.46) | KMT2AHTR6MAPTTSHRGAA | |
| SCHEMBL6929151 | 0.83 | GAA (0.40) | KMT2ASMN1; SMN2HTTGAALMNA | |
| SCHEMBL5850131 | 0.83 | HTR6 (0.41) | KMT2AHTR6GAALMNAALDH1A1 | |
| SCHEMBL3127290 | 0.82 | CA12 (0.40) | KMT2ASMN1; SMN2HTTGAALMNA | |
| SCHEMBL3132636 | 0.82 | GAA (0.40) | KMT2ASMN1; SMN2HTTMAPTTSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL1809323 | 0.81 | ACHE (0.39) | KMT2AHTR6HTTTSHRLMNA | |
| SCHEMBL7133269 | 0.81 | CA12 (0.47) | KMT2ASMN1; SMN2HTTGAALMNA | |
| SCHEMBL64189 | 0.81 | CA12 (0.47) | KMT2ASMN1; SMN2HTTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984473-B2 | Light blocking; amplified photoresist; acid generators; high density semiconductors | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 2006-01-10 | — | — | US | disclosed |
| US-20030152845-A1 | Mask blank, protective film therefor and method of patterning mask blank | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 2003-08-14 | — | — | US | disclosed |