Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28224269 | 0.87 | KMT2A (0.49) | KMT2AMMP2MMP9NAALAD2L3MBTL1 | |
| SCHEMBL4159914 | 0.76 | KMT2A (0.49) | KMT2AMMP2MMP9NAALAD2L3MBTL1 | |
| SCHEMBL10620657 | 0.76 | MME (0.50) | MMETACR3 | |
| SCHEMBL20133728 | 0.75 | TACR3 (0.43) | KMT2AMMERPS6KB1TACR3AOC3 | |
| SCHEMBL1663305 | 0.75 | NAALAD2 (0.54) | MMP9NAALAD2CA2CA1 | |
| SCHEMBL12002454 | 0.75 | NAALAD2 (0.54) | MMP9NAALAD2CA2CA1 | |
| SCHEMBL11638197 | 0.75 | AOC3 (0.48) | KMT2ARPS6KB1TACR3AOC3MAPT | |
| SCHEMBL7604126 | 0.74 | KMT2A (0.41) | KMT2AMMP2MMP9NAALAD2L3MBTL1 | |
| SCHEMBL1955325 | 0.74 | LMNA (0.50) | RPS6KB1TACR3AOC3 | |
| SCHEMBL402068 | 0.74 | KMT2A (0.53) | KMT2AMMP2MMP9MMENAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987131-B1 | Phenylacetic acid compositions for treating or preventing hypercholesterolemia | BURZYNSKI STANISLAW R | 2006-01-17 | — | — | US | claimed |
| EP-1206936-B1 | Phenylacetic acid compositions for treating or preventing hypercholesterolemia | BURZYNSKI STANISLAW R (US) | 2005-08-24 | — | — | EP | claimed |
| EP-1206936-A2 | Phenylacetic acid compositions for treating or preventing hypercholesterolemia | BURZYNSKI, Stanislaw R. (US) | 2002-05-22 | — | — | EP | claimed |
| US-6987131-B1 | Phenylacetic acid compositions for treating or preventing hypercholesterolemia | BURZYNSKI STANISLAW R | 2006-01-17 | — | — | US | disclosed |
| EP-1206936-B1 | Phenylacetic acid compositions for treating or preventing hypercholesterolemia | BURZYNSKI STANISLAW R (US) | 2005-08-24 | — | — | EP | disclosed |
| EP-1206936-A2 | Phenylacetic acid compositions for treating or preventing hypercholesterolemia | BURZYNSKI, Stanislaw R. (US) | 2002-05-22 | — | — | EP | disclosed |