Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2310258 | 0.78 | KDM4E (0.51) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL2309179 | 0.78 | KDM4E (0.51) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL8828077 | 0.76 | KDM4E (0.58) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL9264392 | 0.75 | DAO (0.64) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL31422853 | 0.73 | CNR2 (0.44) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL12167565 | 0.71 | KDM4E (1.00) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL14502609 | 0.70 | XDH (0.37) | KDM4EHSD17B10HPGDALDH1A1POLB | |
| SCHEMBL9386315 | 0.70 | KDM4E (0.42) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL2808417 | 0.69 | DHODH (0.58) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL29415464 | 0.69 | DHODH (0.58) | KDM4EHSD17B10HPGDGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417132-A2 | HERBICIDAL QUINOLINE AND 1,8-NAPHTHYRIDINE COMPOUNDS | Syngenta Limited (GB) | 2012-02-15 | — | — | EP | claimed |
| WO-2010116122-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-10-14 | — | — | WO | claimed |