Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2150226 | 0.94 | ACHE (0.46) | ACHEINPP5AMMP2MMP8NPSR1 | |
| SCHEMBL18486452 | 0.92 | ACHE (0.50) | ACHEINPP5AMMP2MMP8NPSR1 | |
| SCHEMBL15105606 | 0.92 | ACHE (0.50) | ACHEINPP5AMMP2MMP8NPSR1 | |
| SCHEMBL270557 | 0.92 | ACHE (0.50) | ACHEINPP5AMMP2MMP8NPSR1 | |
| SCHEMBL5850409 | 0.88 | INPP5A (0.44) | ACHEINPP5AFDPSSMPD1 | |
| SCHEMBL6835509 | 0.84 | ACHE (0.43) | ACHEINPP5AMMP2MMP8NPSR1 | |
| Methane SCHEMBL8333017 | 0.84 | FDPS (0.38) | ACHEINPP5ANPSR1MEN1KMT2A | |
| SCHEMBL2238021 | 0.83 | — | — | |
| SCHEMBL269924 | 0.82 | ACHE (0.47) | ACHEINPP5AMMP2MMP8NPSR1 | |
| SCHEMBL20099365 | 0.80 | ACHE (0.45) | ACHEINPP5AMMP2NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153901-B2 | Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production | ALBEMARLE CORPORATION (US) | 2006-12-26 | — | — | US | disclosed |
| EP-1685176-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005052018-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050113495-A1 | Flame retardant, additive compositions, and flame retardant polyurethanes | ALBEMARLE CORPORATION | 2005-05-26 | — | — | US | disclosed |