SCHEMBL5852291

SCHEMBL5852291

S=P(OCl)(Oc1c(Cl)cccc1Cl)Oc1c(Cl)cccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
LMNA P02545 2/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5852286 0.77 LMNA (0.38) KMT2ACYP1A2CYP2A6LMNATSHR
SCHEMBL5850655 0.77 ALDH1A1 (0.34) KMT2ACYP1A2CYP2A6LMNATSHR
SCHEMBL5850892 0.76 CYP2A6 (0.44) CYP1A2CYP2A6LMNATSHRSMN1; SMN2
SCHEMBL3230150 0.72 LMNA (0.52) KMT2ALMNATSHRSMN1; SMN2
SCHEMBL8329919 0.70 SMN1; SMN2 (0.43) KMT2ACYP1A2CYP2A6LMNATSHR
SCHEMBL5850893 0.68 SRC (0.43) KMT2ATSHR
SCHEMBL10483778 0.68 SMN1; SMN2 (0.42) KMT2ACYP1A2CYP2A6LMNATSHR
SCHEMBL11775924 0.67 KMT2A (0.37) KMT2ASMN1; SMN2
SCHEMBL5850515 0.67 MEN1 (0.48) KMT2ACYP1A2CYP2A6LMNATSHR
SCHEMBL25222316 0.67 INPPL1 (0.59) KMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7153901-B2 Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production ALBEMARLE CORPORATION (US) 2006-12-26 US disclosed
EP-1685176-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2006-08-02 EP disclosed
WO-2005052018-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2005-06-09 WO disclosed
US-20050113495-A1 Flame retardant, additive compositions, and flame retardant polyurethanes ALBEMARLE CORPORATION 2005-05-26 US disclosed