SCHEMBL5851114

SCHEMBL5851114

OC1(O)C=Nc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.35
PDK2 Q15119 2/20 0.32
THRB P10828 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5486167 0.77 HTR5A (0.33) ADORA3PDK2TDP1
SCHEMBL5674182 0.77 ADORA3 (0.33) ADORA3PDK2
SCHEMBL3124906 0.77 ADORA3 (0.33) ADORA3PDK2
SCHEMBL14575103 0.77 ADORA3 (0.33) ADORA3PDK2
SCHEMBL28499297 0.76 ADORA3 (0.33) ADORA3
SCHEMBL28806304 0.74 P2RX1 (0.35) ADORA3THRBTDP1
SCHEMBL926937 0.71 HTR5A (0.35) PDK2TDP1
SCHEMBL30876182 0.71
SCHEMBL29639106 0.71 HTR5A (0.35) PDK2TDP1
SCHEMBL28886117 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109897064-B Preparation method of 3-indolyl-3- (phosphodiethyl) oxoindole compound 吉林大学 2021-04-06 CN claimed
CN-112047951-A Chiral spiro [ pyrrole-2, 2' -furan ] compound and preparation method thereof 吉林大学 2020-12-08 CN claimed
CN-103827089-A Novel compound having angiogenesis inhibitory activity, method for preparing same, and pharmaceutical composition comprising same BORYUNG PHARM 2014-05-28 CN claimed
CN-115819482-A Processing method for making kalanchoe leaf as water-soluble indole glycoside extraction raw material 江苏本草新萃生物科技有限公司 2023-03-21 CN disclosed
CN-114869924-A Stable-state treatment and processing method for fresh stem and leaf alkaloids of Strychnos incarnata 中国林业科学研究院林产化学工业研究所 2022-08-09 CN disclosed
CN-109897064-B Preparation method of 3-indolyl-3- (phosphodiethyl) oxoindole compound 吉林大学 2021-04-06 CN disclosed
CN-109897064-B Preparation method of 3-indolyl-3- (phosphodiethyl) oxoindole compound 吉林大学 2021-04-06 CN disclosed
CN-103827089-A Novel compound having angiogenesis inhibitory activity, method for preparing same, and pharmaceutical composition comprising same BORYUNG PHARM 2014-05-28 CN disclosed
CN-102438830-A Low temperature impact resistant coextruded films BAYER MATERIALSCIENCE AG LAW A 2012-05-02 CN disclosed
CN-101842235-A Method for producing a polycarbonate multilayer composite BAYER MATERIALSCIENCE AG 2010-09-22 CN disclosed
CN-101842234-A Method for producing polycarbonate multilayer composites BAYER MATERIALSCIENCE AG 2010-09-22 CN disclosed
CN-101842448-A Method for producing polycarbonate multilayer composites BUNDESDRUCKEREI GMBH 2010-09-22 CN disclosed
US-7067592-B2 Thermoplastic elastomer composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2006-06-27 US disclosed
US-6809157-B2 RECYCLE PROPERTY IN THAT PHYSICAL PROPERTIES DO NOT DETERIORATE EVEN THOUGH FORMATION OF CROSSLINKING AND DISSOCIATION OF CROSSLINKING ARE REPEATEDLY CONDUCTED WITH ALTERING TEMPERATURE THE YOKOHAMA RUBBER CO., LTD. (JP) 2004-10-26 US disclosed
US-20040106744-A1 Thermoplastic elastomer composition YOKOHAMA RUBBER CO., LTD., THE (JP) 2004-06-03 US disclosed
US-20040010090-A1 Thermoplastic elastomer composition YOKOHAMA RUBBER CO., LTD., THE (JP) 2004-01-15 US disclosed
US-20020022700-A1 Thermoplastic polymer and thermoplastic elastomer composition THE YOKOHAMA RUBBER CO., LTD. 2002-02-21 US disclosed