Acetic Acid

Acetic Acid

SCHEMBL5852185

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nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.89
CA4 P22748 3/20 0.58
LMNA P02545 2/20 0.50
TSHR P16473 2/20 0.46
THPO P40225 1/20 0.46
FFAR3 O14843 1/20 0.46
LCK P06239 1/20 0.46
FYN P06241 1/20 0.46
ALOX15 P16050 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
FAHD1 Q6P587 1/20 0.42
ALDH1A1 P00352 4/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CA2 P00918 1/20 0.36
PTGS1 P23219 1/20 0.36
MMP12 P39900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL54008 1.00
Acetic Acid SCHEMBL2345031 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL363369 0.95
Acetic Acid SCHEMBL11171211 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL9789818 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL600693 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL60673 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL38064 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL15659684 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL7940740 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12060314-B2 Branched alcohols formed from vinylidene olefins by hydroformylation and methods for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-08-13 US disclosed
CN-116059380-A Composition for upper respiratory tract administration and administration method thereof 原创生医股份有限公司 2023-05-05 CN disclosed
US-20220306558-A1 Branched Alcohols Formed from Vinylidene Olefins by Hydroformylation and Methods for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2022-09-29 US disclosed
WO-2022085746-A1 METHOD FOR PRODUCING FLUORENONE 三菱瓦斯化学株式会社 2022-04-28 WO disclosed
US-11292969-B2 Catalyst and method related thereto for synthesis of hydrocarbons from syngas SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-04-05 US disclosed
US-6998101-B2 Crystallized IM-8 solid of metallophosphate type and process for the preparation thereof INSTITUT FRANCAIS DU PETROLE (FR) 2006-02-14 US disclosed
US-20040258600-A1 Crystallised IM-8 solid of metallophosphate type and process for the preparation thereof INSTITUT FRANCAIS DU PETROLE (FR) 2004-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220306558-A1 Branched Alcohols Formed from Vinylidene Olefins by Hydroformylation and Methods for Production Thereof ADH1A, ADH1C, ADH5 CA1 957/4885CA4 692/4885LMNA 4198/4885
US-12060314-B2 Branched alcohols formed from vinylidene olefins by hydroformylation and methods for production thereof ADH1A, ADH1C, ADH5 CA1 957/4885CA4 692/4885LMNA 4198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.