Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 12/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 12/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.43 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.41 |
| ▸ | GLRB | P48167 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1278249 | 0.91 | LMNA (0.46) | CYP2C9CYP2C19CYP1A2AKR1C3AKR1C2 | |
| SCHEMBL30040652 | 0.84 | CYP1A2 (0.42) | CYP2C9CYP2C19CYP1A2GLRA3GLRB | |
| SCHEMBL7257754 | 0.82 | CYP2C9 (0.53) | CYP2C9CYP2C19CYP1A2GLRA3GLRB | |
| SCHEMBL27283013 | 0.82 | CYP2C9 (0.46) | CYP2C9CYP2C19CYP1A2GLRA3GLRB | |
| SCHEMBL11689866 | 0.81 | CYP2C9 (0.52) | CYP2C9CYP2C19CYP1A2GLRA3GLRB | |
| SCHEMBL7108121 | 0.80 | CYP1A2 (0.50) | CYP2C9CYP2C19CYP1A2AKR1C3AKR1C2 | |
| SCHEMBL8987705 | 0.80 | CYP1A2 (0.50) | CYP2C9CYP2C19CYP1A2GLRA3GLRB | |
| SCHEMBL8987698 | 0.80 | CYP1A2 (0.50) | CYP2C9CYP2C19CYP1A2GLRA3GLRB | |
| SCHEMBL283603 | 0.80 | CYP1A2 (0.50) | CYP2C9CYP2C19CYP1A2AKR1C3AKR1C2 | |
| SCHEMBL29408356 | 0.80 | CYP1A2 (0.50) | CYP2C9CYP2C19CYP1A2AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153901-B2 | Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production | ALBEMARLE CORPORATION (US) | 2006-12-26 | — | — | US | disclosed |
| EP-1685176-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005052018-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050113495-A1 | Flame retardant, additive compositions, and flame retardant polyurethanes | ALBEMARLE CORPORATION | 2005-05-26 | — | — | US | disclosed |
| US-20040171722-A1 | Flame retardant polyurethanes and additive compositions for use in producing them | ALBEMARLE CORPORATION | 2004-09-02 | — | — | US | disclosed |