Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.44 |
| ▸ | GLRB | P48167 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987698 | 1.00 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19GLRA3GLRB | |
| SCHEMBL11444175 | 0.90 | GLRA3 (0.50) | GLRA3GLRBALDH1A1SMN1; SMN2CA2 | |
| SCHEMBL11689866 | 0.85 | CYP2C9 (0.52) | CYP1A2CYP2C9CYP2C19GLRA3GLRB | |
| SCHEMBL8987771 | 0.84 | LMNA (0.46) | CYP1A2CYP2C9CA2MEN1KMT2A | |
| SCHEMBL8091137 | 0.84 | LMNA (0.46) | CYP1A2CYP2C9CA2MEN1KMT2A | |
| SCHEMBL7108121 | 0.83 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19GLRA3GLRB | |
| SCHEMBL283603 | 0.83 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19GLRA3GLRB | |
| SCHEMBL29408356 | 0.83 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19GLRA3GLRB | |
| SCHEMBL38652043 | 0.82 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19GLRA3GLRB | |
| SCHEMBL5852243 | 0.80 | CYP2C9 (0.46) | CYP1A2CYP2C9CYP2C19GLRA3GLRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488117-A | FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| US-5369159-A | Heat, oxidation and radiation resistance for polymers | CIBA-GEIGY CORPORATION (US) | 1994-11-29 | — | — | US | disclosed |