Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5853019

C[SiH](C)[Hf+2](NC(=O)c1ccccc1)C1=CC=CC1.[Cl-].[Cl-]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
IDO1 P14902 1/20 0.35
ALOX15 P16050 1/20 0.35
HDAC1 Q13547 1/20 0.35
CA9 Q16790 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
NCOR2 Q9Y618 1/20 0.35
KMT2A Q03164 2/20 0.35
GAA P10253 3/20 0.34
MAPT P10636 2/20 0.34
LMNA P02545 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5852749 0.86 HDAC8 (0.44) HDAC8HDAC6KMT2ALMNASMN1; SMN2
Hydrochloric Acid SCHEMBL5852901 0.83 HPGD (0.39) ALOX15MAPTSMN1; SMN2NPC1RAB9A
Hydrochloric Acid SCHEMBL5855476 0.82 POLB (0.36) HDAC3HDAC1HDAC7HDAC2HDAC8
Hydrochloric Acid SCHEMBL5853061 0.81 L3MBTL1 (0.34) NPC1RAB9ATYK2
Hydrochloric Acid SCHEMBL5854098 0.81 ITGB1 (0.34) GAALMNA
Hydrochloric Acid SCHEMBL5852577 0.79 ITGB1 (0.34) KMT2ALMNASMN1; SMN2
Hydrochloric Acid SCHEMBL5854471 0.78 SMN1; SMN2 (0.35) HDAC3CA12CA1IDO1ALOX15
Hydrochloric Acid SCHEMBL5853498 0.76 TAS1R3 (0.37) KMT2A
Hydrochloric Acid SCHEMBL6832127 0.75
Hydrochloric Acid SCHEMBL5854057 0.71 HPGD (0.34) HDAC3HDAC1HDAC7HDAC2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed