Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5853656 | 0.90 | LMNA (0.33) | LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5853577 | 0.88 | KCNK3 (0.32) | KCNK3KCNK9LMNAKMT2ABCL2 | |
| Hydrochloric Acid SCHEMBL5853875 | 0.86 | HPGD (0.37) | LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL5854705 | 0.84 | PPIA (0.31) | LMNA | |
| Hydrochloric Acid SCHEMBL5853979 | 0.82 | MEN1 (0.34) | LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5854286 | 0.80 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL5853273 | 0.80 | P2RX4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL5852852 | 0.79 | TAS1R3 (0.36) | — | |
| Hydrochloric Acid SCHEMBL5854113 | 0.79 | KCNK3 (0.36) | KCNK3KCNK9LMNAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL6847745 | 0.79 | LMNA (0.31) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |