Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5852852 | 0.91 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2 | |
| Hydrochloric Acid SCHEMBL5855541 | 0.88 | KMT2A (0.35) | KMT2ATAS1R3TAS1R1TAS1R2TP53 | |
| Hydrochloric Acid SCHEMBL5856903 | 0.87 | POLB (0.35) | KMT2A | |
| Hydrochloric Acid SCHEMBL5853875 | 0.84 | HPGD (0.37) | — | |
| Hydrochloric Acid SCHEMBL5852854 | 0.83 | SMN1; SMN2 (0.42) | KMT2A | |
| Hydrochloric Acid SCHEMBL5853979 | 0.82 | MEN1 (0.34) | KMT2A | |
| Hydrochloric Acid SCHEMBL5853656 | 0.81 | LMNA (0.33) | KMT2A | |
| Hydrochloric Acid SCHEMBL5854286 | 0.80 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL5853181 | 0.79 | KMT2A (0.40) | KMT2ATAS1R3TAS1R1TAS1R2TP53 | |
| Hydrochloric Acid SCHEMBL5855372 | 0.79 | TAS1R3 (0.34) | TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |