Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 3/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5853597 | 0.88 | PPIA (0.40) | PPIAITGB1ITGA4GAALMNA | |
| Hydrochloric Acid SCHEMBL5853357 | 0.87 | HPGD (0.40) | GAAKMT2A | |
| Hydrochloric Acid SCHEMBL5855851 | 0.85 | BCL2 (0.36) | PPIAGAALMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5853382 | 0.83 | CCKBR (0.33) | GAALMNAKMT2AMEN1HDAC3 | |
| Hydrochloric Acid SCHEMBL5852952 | 0.82 | GAA (0.38) | GAALMNAKMT2AMEN1HDAC3 | |
| Hydrochloric Acid SCHEMBL5854682 | 0.81 | NR1H4 (0.39) | GAALMNAKMT2AMEN1HDAC3 | |
| Hydrochloric Acid SCHEMBL5855900 | 0.81 | POLB (0.37) | GAALMNAKMT2AMEN1HDAC3 | |
| Hydrochloric Acid SCHEMBL7092701 | 0.80 | POLB (0.32) | GAALMNA | |
| Hydrochloric Acid SCHEMBL5856047 | 0.80 | ITGB1 (0.30) | ITGB1ITGA4 | |
| Hydrochloric Acid SCHEMBL5853874 | 0.80 | TAS1R3 (0.37) | PPIAGAALMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |