Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101732 | 0.84 | TDP1 (0.48) | ALDH1A1CYP3A4CA2MAPK1LMNA | |
| SCHEMBL6675432 | 0.80 | TSHR (0.58) | ALDH1A1CYP3A4CA2MAPK1LMNA | |
| SCHEMBL5853813 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CA2MAPK1LMNA | |
| SCHEMBL5853805 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CA2MAPK1LMNA | |
| SCHEMBL890675 | 0.78 | TSHR (0.69) | ALDH1A1CYP3A4CA2MAPK1LMNA | |
| SCHEMBL9115198 | 0.78 | TSHR (0.69) | ALDH1A1CYP3A4CA2MAPK1LMNA | |
| SCHEMBL1275661 | 0.78 | TSHR (0.69) | ALDH1A1CYP3A4CA2MAPK1LMNA | |
| SCHEMBL10585558 | 0.78 | TSHR (0.69) | ALDH1A1CYP3A4CA2MAPK1LMNA | |
| SCHEMBL8962376 | 0.78 | TSHR (0.69) | ALDH1A1CYP3A4CA2MAPK1LMNA | |
| Styrene SCHEMBL1246542 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CA2MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989430-B2 | High refractive index aromatic-based siloxane monofunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2006-01-24 | — | — | US | disclosed |