Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101738 | 0.86 | TDP1 (0.46) | ALDH1A1CA2LMNATSHRTDP1 | |
| SCHEMBL6675432 | 0.80 | TSHR (0.58) | ALDH1A1CYP3A4CA2LMNAMAPK1 | |
| SCHEMBL5853807 | 0.78 | ALDH1A1 (0.48) | ALDH1A1CYP3A4CA2LMNAMAPK1 | |
| SCHEMBL5853805 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CA2LMNAMAPK1 | |
| SCHEMBL9115198 | 0.77 | TSHR (0.69) | ALDH1A1CYP3A4CA2LMNAMAPK1 | |
| SCHEMBL1275661 | 0.77 | TSHR (0.69) | ALDH1A1CYP3A4CA2LMNAMAPK1 | |
| SCHEMBL8962376 | 0.77 | TSHR (0.69) | ALDH1A1CYP3A4CA2LMNAMAPK1 | |
| SCHEMBL10585558 | 0.77 | TSHR (0.69) | ALDH1A1CYP3A4CA2LMNAMAPK1 | |
| SCHEMBL890675 | 0.77 | TSHR (0.69) | ALDH1A1CYP3A4CA2LMNAMAPK1 | |
| Styrene SCHEMBL1246542 | 0.77 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CA2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989430-B2 | High refractive index aromatic-based siloxane monofunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2006-01-24 | — | — | US | disclosed |