Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5856711 | 0.99 | HSP90AA1 (0.36) | NAAAHSP90AA1P2RX7FAAHSOAT1 | |
| Hydrochloric Acid SCHEMBL5854811 | 0.99 | HSP90AA1 (0.36) | NAAAHSP90AA1P2RX7FAAHSOAT1 | |
| Hydrochloric Acid SCHEMBL5855270 | 0.96 | ALDH1A1 (0.32) | POLBALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5854170 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL5854185 | 0.80 | HSP90AA1 (0.35) | NAAAHSP90AA1FAAHSOAT1LMNA | |
| Hydrochloric Acid SCHEMBL5855751 | 0.79 | HSP90AA1 (0.37) | NAAAHSP90AA1FAAHSOAT1LMNA | |
| Hydrochloric Acid SCHEMBL5852782 | 0.79 | HSP90AA1 (0.37) | NAAAHSP90AA1FAAHSOAT1LMNA | |
| Hydrochloric Acid SCHEMBL5854293 | 0.75 | ALDH1A1 (0.32) | NAAAALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5852786 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL5853387 | 0.73 | SMN1; SMN2 (0.37) | LMNAPOLBALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |