Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5852782 | 1.00 | HSP90AA1 (0.37) | HSP90AA1NAAAFAAHCCR2EPHX2 | |
| Hydrochloric Acid SCHEMBL5854185 | 0.99 | HSP90AA1 (0.35) | HSP90AA1NAAAFAAHCCR2EPHX2 | |
| Hydrochloric Acid SCHEMBL5854293 | 0.95 | ALDH1A1 (0.32) | NAAA | |
| Hydrochloric Acid SCHEMBL5856452 | 0.89 | TP53 (0.31) | LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5856711 | 0.80 | HSP90AA1 (0.36) | HSP90AA1NAAAFAAHEPHX2SOAT1 | |
| Hydrochloric Acid SCHEMBL5854811 | 0.80 | HSP90AA1 (0.36) | HSP90AA1NAAAFAAHEPHX2SOAT1 | |
| Hydrochloric Acid SCHEMBL5853889 | 0.79 | NAAA (0.33) | HSP90AA1NAAAFAAHEPHX2SOAT1 | |
| Hydrochloric Acid SCHEMBL5852710 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL5855270 | 0.74 | ALDH1A1 (0.32) | POLB | |
| Hydrochloric Acid SCHEMBL5853377 | 0.72 | HSP90AA1 (0.37) | HSP90AA1NAAAFAAHEPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |