Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449423 | 1.00 | TSHR (0.56) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL5854164 | 1.00 | TSHR (0.56) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4449427 | 0.92 | HCAR2 (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4449421 | 0.92 | HCAR2 (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4565814 | 0.92 | HCAR2 (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL28034846 | 0.88 | TSHR (0.48) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL5973483 | 0.88 | ATM (0.50) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7636692 | 0.88 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL5973493 | 0.88 | ATM (0.50) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7638858 | 0.88 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957079-B1 | ETHER COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | SHOWA DENKO KK (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-7038076-B2 | Fumarate derivative, method for producing the same | SHOWA DENKO K.K. (JP) | 2006-05-02 | — | — | US | disclosed |
| EP-1301461-A2 | FUMARATE DERIVATIVE, METHOD FOR PRODUCING THE SAME | Showa Denko K.K. (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-20030060563-A1 | Fumarate derivative, method for producing the same | SHOWA DENKO K.K. (JP) | 2003-03-27 | — | — | US | disclosed |
| WO-2003010124-A1 | POLYMERIZABLE COMPOUND, polymeRIZABLE COMPOSITION AND CURED PRODUCT CONTAINING THE COMPOUND | SHOWA DENKO K. K. (JP) | 2003-02-06 | — | — | WO | disclosed |
| US-6376702-B1 | A 1-ALKENYL ETHER | SHOWA DENKO K.K. (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1176136-A1 | PROCESS FOR PRODUCING FUMARIC ESTER | Showa Denko K.K. (JP) | 2002-01-30 | — | — | EP | disclosed |
| WO-2002006206-A2 | FUMARATE DERIVATIVE, METHOD FOR PRODUCING THE SAME | SHOWA DENKO K.K. (JP) | 2002-01-24 | — | — | WO | disclosed |
| US-20020002306-A1 | Method for producing fumaric acid esters | SHOWA DENKO K.K. (JP) | 2002-01-03 | — | — | US | disclosed |
| US-6204410-B1 | FOR FREE RADICAL POLYMERIZATION | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2001-03-20 | — | — | US | disclosed |
| EP-0957079-A1 | NEW ETHER COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | Showa Denko Kabushiki Kaisha (JP) | 1999-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002306-A1 | Method for producing fumaric acid esters | FH, ME1, ME3 | TSHR 4711/4885ALDH1A1 569/4885TP53 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.