SCHEMBL5854367

SCHEMBL5854367

Cc1ccccc1C(=O)N[Zr](Cl)(Cl)(C1C=Cc2ccccc21)[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.36
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 5/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
DHODH Q02127 1/20 0.32
KCNK3 O14649 1/20 0.32
KCNK9 Q9NPC2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RECQL P46063 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CSF1R P07333 1/20 0.32
FLT1 P17948 1/20 0.32
FLT4 P35916 1/20 0.32
KDR P35968 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5853753 0.89 TAS1R3 (0.34) L3MBTL1
SCHEMBL5852517 0.88 NPC1 (0.38) HPGDNPC1RAB9ASMN1; SMN2POLB
SCHEMBL5856585 0.87 KCNK3 (0.31) KCNK3KCNK9
SCHEMBL5853102 0.86 ITGB1 (0.31)
SCHEMBL5853044 0.85 ATM (0.32)
SCHEMBL5854061 0.85 KMT2A (0.32)
SCHEMBL5856493 0.84 MEN1 (0.31) HPGDALDH1A1
SCHEMBL5853963 0.84 POLB (0.33) SMN1; SMN2POLB
SCHEMBL5856523 0.82 SMN1; SMN2 (0.41) NPC1RAB9ASMN1; SMN2POLBKCNK3
SCHEMBL5855913 0.81 ALDH1A1 (0.34) POLBGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed