SCHEMBL5856523

SCHEMBL5856523

Cc1cccc(C(=O)N[Zr](Cl)(Cl)(C2C=Cc3ccccc32)[SiH](c2ccccc2)c2ccccc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.41
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
POLB P06746 2/20 0.39
KCNK3 O14649 2/20 0.39
KCNK9 Q9NPC2 2/20 0.39
MAPT P10636 3/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
LMNA P02545 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
OPRM1 P35372 1/20 0.37
OPRK1 P41145 1/20 0.37
NPC1 O15118 4/20 0.37
RAB9A P51151 4/20 0.37
KAT6A Q92794 1/20 0.36
KCNH2 Q12809 1/20 0.36
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5853963 0.92 POLB (0.33) SMN1; SMN2MEN1KMT2APOLBLMNA
SCHEMBL5853044 0.89 ATM (0.32) MEN1KMT2AHDAC8HDAC6LMNA
SCHEMBL5854537 0.89 SMN1; SMN2 (0.41) SMN1; SMN2MEN1KMT2APOLBKCNK3
SCHEMBL5854082 0.87 NR1H4 (0.36) SMN1; SMN2MEN1KMT2AKCNK3KCNK9
SCHEMBL5854061 0.84 KMT2A (0.32) MEN1KMT2A
SCHEMBL5853753 0.84 TAS1R3 (0.34) L3MBTL1
SCHEMBL5854367 0.82 HPGD (0.36) SMN1; SMN2POLBKCNK3KCNK9NPC1
SCHEMBL5856493 0.81 MEN1 (0.31) MEN1KMT2AMAPTALDH1A1
SCHEMBL5853098 0.80 POLB (0.33) SMN1; SMN2MEN1KMT2APOLBLMNA
SCHEMBL5852913 0.80 LMNA (0.33) KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed