SCHEMBL5854522

SCHEMBL5854522

O=C(O)c1ccc(-c2ccc(OCCCCCCO)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.74
TP53 P04637 1/20 0.66
TSHR P16473 1/20 0.66
PLA2G4B P0C869 6/20 0.64
HTT P42858 3/20 0.60
PKM P14618 1/20 0.59
PLA2G4A P47712 1/20 0.57
PTPN11 Q06124 1/20 0.57
POLB P06746 1/20 0.56
APEX1 P27695 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
ALDH1A1 P00352 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8636286 1.00 RARB (0.74) RARBTP53TSHRPLA2G4BHTT
SCHEMBL10408397 1.00 RARB (0.74) RARBTP53TSHRPLA2G4BHTT
SCHEMBL10408458 1.00 RARB (0.74) RARBTP53TSHRPLA2G4BHTT
SCHEMBL9449719 1.00 RARB (0.74) RARBTP53TSHRPLA2G4BHTT
SCHEMBL6261667 1.00 RARB (0.74) RARBTP53TSHRPLA2G4BHTT
SCHEMBL14346716 0.98 RARB (0.71) RARBTP53TSHRPLA2G4BHTT
SCHEMBL9221792 0.95 TP53 (0.72) RARBTP53TSHRPLA2G4BHTT
SCHEMBL223467 0.95 TP53 (0.72) RARBTP53TSHRPLA2G4BHTT
SCHEMBL4653588 0.95 TP53 (0.72) RARBTP53TSHRPLA2G4BHTT
SCHEMBL5478282 0.95 TP53 (0.72) RARBTP53TSHRPLA2G4BHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3894514-A1 MESOGEN COMPOUNDS Transitions Optical, Ltd. (IE) 2021-10-20 EP disclosed
WO-2020120282-A1 MESOGEN COMPOUNDS TRANSITIONS OPTICAL, LTD. (IE) 2020-06-18 WO disclosed
EP-2330173-B1 A RADIAL TYPE LIQUID CRYSTAL COMPOUND, AND AN OPTICAL FILM AND LIQUID CRYSTAL DISPLAY (LCD) DEVICE CONTAINING COMPOUND LG CHEMICAL LTD (KR) 2016-08-17 EP disclosed
US-9120883-B2 Polymerizable compound having lateral substituent in terminal ring structure DIC CORPORATION (JP) 2015-09-01 US disclosed
US-9120883-B2 Polymerizable compound having lateral substituent in terminal ring structure DIC CORPORATION (JP) 2015-09-01 US disclosed
US-20140080990-A1 POLYMERIZABLE COMPOUND HAVING LATERAL SUBSTITUENT IN TERMINAL RING STRUCTURE DIC CORPORATION (JP) 2014-03-20 US disclosed
US-20140080990-A1 POLYMERIZABLE COMPOUND HAVING LATERAL SUBSTITUENT IN TERMINAL RING STRUCTURE DIC CORPORATION (JP) 2014-03-20 US disclosed
US-8471055-B2 Photo-crosslinkable liquid crystal monomers with optical activity CHUNGHWA PICTURE TUBES, LTD. (TW) 2013-06-25 US disclosed
US-8339567-B2 Radial-shaped liquid crystal compound, and optical film and liquid crystal display device comprising the same LG CHEM, LTD. (KR) 2012-12-25 US disclosed
US-20120298932-A1 METAL COMPLEX, COMPOSITION COMPRISING SAME AND LIGHT-EMITTING ELEMENT USING SAME TOKYO INSTITUTE OF TECHNOLOGY (JP) 2012-11-29 US disclosed
US-20120289731-A1 PHOTO-CROSSLINKABLE LIQUID CRYSTAL MONOMERS WITH OPTICAL ACTIVITY NATIONAL CHIAO TUNG UNIVERSITY (TW) 2012-11-15 US disclosed
EP-2460788-A1 METAL COMPLEX, COMPOSITION COMPRISING SAME AND LIGHT-EMITTING ELEMENT USING SAME Sumitomo Chemical Company, Limited (JP) 2012-06-06 EP disclosed
US-20110181826-A1 RADIAL-SHAPED LIQUID CRYSTAL COMPOUND, AND OPTICAL FILM AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2011-07-28 US disclosed
EP-2330173-A2 A RADIAL TYPE LIQUID CRYSTAL COMPOUND, AND AN OPTICAL FILM AND LIQUID CRYSTAL DISPLAY (LCD) DEVICE CONTAINING COMPOUND LG Chem, Ltd. (KR) 2011-06-08 EP disclosed
US-7001648-B2 Glassy chiral-nematic liquid crystals and optical devices containing same UNIVERSITY OF ROCHESTER (US) 2006-02-21 US disclosed
US-20050263741-A1 GLASSY CHIRAL-NEMATIC LIQUID CRYSTALS AND OPTICAL DEVICES CONTAINING SAME NATIONAL SCIENCE FOUNDATION 2005-12-01 US disclosed
WO-2004083335-A2 GLASSY CHIRAL-NEMATIC LIQUID CRYSTALS AND OPTICAL DEVICES CONTAINING SAME UNIVERSITY OF ROCHESTER (US) 2004-09-30 WO disclosed
US-4833035-A Oriented polymer materials MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-05-23 US disclosed
US-4822682-A Oriented polymer materials MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120289731-A1 PHOTO-CROSSLINKABLE LIQUID CRYSTAL MONOMERS WITH OPTICAL ACTIVITY UACA, DLK1, DECR1 RARB 1613/4885TP53 3405/4885TSHR 4143/4885
US-20140080990-A1 POLYMERIZABLE COMPOUND HAVING LATERAL SUBSTITUENT IN TERMINAL RING STRUCTURE MKI67, CCNI, LAS1L RARB 4114/4885TP53 4696/4885TSHR 4685/4885
US-20110181826-A1 RADIAL-SHAPED LIQUID CRYSTAL COMPOUND, AND OPTICAL FILM AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING THE SAME CXCR1, NLRP1, RCC1 RARB 1547/4885TP53 3428/4885TSHR 3705/4885
US-20120298932-A1 METAL COMPLEX, COMPOSITION COMPRISING SAME AND LIGHT-EMITTING ELEMENT USING SAME C1S, AP3M1, AP1M1 RARB 3314/4885TP53 2345/4885TSHR 3169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.