SCHEMBL5854556

SCHEMBL5854556

CCC(=O)N[Zr](Cl)(Cl)(C1C=Cc2ccccc21)[SiH](C)C

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RET P07949 1/20 0.31
SIGMAR1 Q99720 2/20 0.30
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5853457 0.90 ALOX5 (0.36) RETMTNR1AMTNR1BMEN1CYP3A4
SCHEMBL5856032 0.88 HTT (0.36) RETMEN1TSHRKMT2A
SCHEMBL5855340 0.87 P2RX7 (0.37) MEN1KMT2A
SCHEMBL5854463 0.87 SIGMAR1 (0.31) SIGMAR1MTNR1AMTNR1BMEN1CYP1A2
SCHEMBL5853751 0.86 P2RX7 (0.39) MEN1KMT2A
SCHEMBL5855689 0.86 P2RX7 (0.39) MEN1KMT2A
SCHEMBL6066827 0.86
SCHEMBL5854772 0.86 BRD4 (0.30)
SCHEMBL6066698 0.83
SCHEMBL5854609 0.82 MEN1 (0.33) MEN1ALOX15MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed