Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.41 |
| ▸ | PPARD | Q03181 | 8/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5854087 | 0.83 | PPARG (0.40) | PPARGPPARDFFAR1PPARAESR1 | |
| SCHEMBL5854567 | 0.82 | FFAR1 (0.39) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL5854636 | 0.81 | L3MBTL1 (0.37) | PPARGPPARDESR1RENHTR2B | |
| SCHEMBL5857617 | 0.76 | PPARG (0.33) | PPARGPPARDFFAR1PPARAESR1 | |
| SCHEMBL5854918 | 0.74 | L3MBTL1 (0.39) | RENTDP1L3MBTL1HTR1A | |
| SCHEMBL7588340 | 0.72 | ESR1 (0.47) | PPARGPPARDFFAR1PPARAESR1 | |
| SCHEMBL2007995 | 0.72 | CYP3A4 (0.46) | PPARGPPARDFFAR1PPARAESR1 | |
| SCHEMBL7589458 | 0.72 | ESR1 (0.46) | PPARGPPARDFFAR1PPARAESR1 | |
| SCHEMBL6900049 | 0.70 | ESR1 (0.55) | PPARGPPARDFFAR1PPARAESR1 | |
| SCHEMBL6901973 | 0.70 | ESR1 (0.55) | PPARGPPARDFFAR1PPARAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074819-B2 | Benzopyran or thiobenzopyran derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-07-11 | — | — | US | disclosed |
| US-6645951-B1 | Antiestrogens for treating breast cancer | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-11-11 | — | — | US | disclosed |
| EP-1087959-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065893-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1999-12-23 | — | — | WO | disclosed |