Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.32 |
| ▸ | NQO2 | P16083 | 6/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128086 | 1.00 | MTNR1A (0.32) | MTNR1AMTNR1BNQO2GAA | |
| SCHEMBL5854225 | 0.93 | ALDH1A1 (0.33) | — | |
| SCHEMBL5854319 | 0.93 | MTNR1A (0.31) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7813218 | 0.91 | SIGMAR1 (0.32) | — | |
| SCHEMBL5856235 | 0.87 | — | — | |
| SCHEMBL6940319 | 0.87 | ESR1 (0.33) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7087556 | 0.87 | ESR1 (0.33) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5856061 | 0.85 | ESR1 (0.40) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5854915 | 0.85 | ESR1 (0.40) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5855627 | 0.84 | MTNR1A (0.32) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074819-B2 | Benzopyran or thiobenzopyran derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-07-11 | — | — | US | disclosed |
| US-6645951-B1 | Antiestrogens for treating breast cancer | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-11-11 | — | — | US | disclosed |
| EP-1087959-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065893-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1999-12-23 | — | — | WO | disclosed |