SCHEMBL1986392

SCHEMBL1986392

CC(C)(C)c1cccc(OCC(=O)O)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.65
LMNA P02545 1/20 0.63
FFAR1 O14842 4/20 0.62
ALOX15 P16050 1/20 0.56
CYP2C19 P33261 1/20 0.55
PPARG P37231 3/20 0.54
PPARD Q03181 2/20 0.54
PTPN7 P35236 1/20 0.51
PPARA Q07869 1/20 0.51
SOD1 P00441 1/20 0.51
ELANE P08246 1/20 0.50
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
CD69 Q07108 1/20 0.50
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA4 P22748 1/20 0.49
CA9 Q16790 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30831879 1.00 SMN1; SMN2 (0.65) SMN1; SMN2LMNAFFAR1ALOX15CYP2C19
SCHEMBL18120698 0.87 SOD1 (0.51) SMN1; SMN2LMNAFFAR1CYP2C19PPARG
SCHEMBL14065575 0.85 KDM4E (0.51) SMN1; SMN2LMNAFFAR1PPARGPPARD
SCHEMBL18231441 0.84 LMNA (0.56) SMN1; SMN2LMNAFFAR1ALOX15PPARG
SCHEMBL12993061 0.84 ALDH1A1 (0.51) SMN1; SMN2LMNAFFAR1CYP2C19PPARG
SCHEMBL31645913 0.83 KDM4E (0.68) LMNAALOX15PPARGPTPN7PPARA
SCHEMBL585546 0.83 KDM4E (0.68) LMNAALOX15PPARGPTPN7PPARA
SCHEMBL3261362 0.83 LMNA (0.55) SMN1; SMN2LMNAFFAR1ALOX15PPARG
SCHEMBL12082548 0.83 SYK (0.58) FFAR1CYP2C19PPARGPPARDSOD1
SCHEMBL4403419 0.83 SMN1; SMN2 (0.55) SMN1; SMN2FFAR1PPARGPPARDSOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112955012-B Compositions comprising pyridine carboxylic acid herbicides and plant growth regulators 科迪华农业科技有限责任公司 2023-05-23 CN claimed
EP-2548434-B1 New tree BVBA CAROLUS C (BE) 2017-12-06 EP claimed
EP-2548433-B1 Nursery fruit tree BVBA CAROLUS C (BE) 2016-02-17 EP claimed
US-20140005049-A1 ACTIVE COMPOUND COMBINATIONS ILG KERSTIN (DE) 2014-01-02 US claimed
EP-2548434-A1 New tree BVBA Carolus C. (BE) 2013-01-23 EP claimed
EP-2548433-A1 Nursery fruit tree BVBA Carolus C. (BE) 2013-01-23 EP claimed
US-20110152077-A1 Active compound combinations BAYER CROPSCIENCE AG (DE) 2011-06-23 US claimed
JP-58203902-A None JP disclosed
CN-117813004-A Auxin herbicide and application method thereof 科迪华农业科技有限责任公司 2024-04-02 CN disclosed
EP-3456178-B1 NURSERY FRUIT TREE OF AT LEAST DOUBLE TRUNK TYPE GRADILIS RECH SARL (FR) 2024-03-13 EP disclosed
CN-112955012-B Compositions comprising pyridine carboxylic acid herbicides and plant growth regulators 科迪华农业科技有限责任公司 2023-05-23 CN disclosed
US-20200275612-A1 NURSERY FRUIT TREE OF AT LEAST DOUBLE TRUNK TYPE GRADILIS RECHERCHE SARL (FR) 2020-09-03 US disclosed
US-10246413-B2 Selective FKBP51 ligands for treatment of psychiatric disorders MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2019-04-02 US disclosed
US-20070191371-A1 HETEROCYCLIC MODULATORS OF PPAR KALYPSYS, INC. (US) 2007-08-16 US disclosed
US-7169936-B2 Indolinone derivatives substituted in the 6-position, their preparation and their use as medicaments BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2007-01-30 US disclosed
US-20070004757-A1 INDOLINE DERIVATIVES SUBSTITUTED IN THE 6 POSITION, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS ROTH GERALD J 2007-01-04 US disclosed
EP-0257063-A4 COMPOSITIONS COMPRISING 1-SUBSTITUTED AZACYCLOALKANES AND THEIR USES. NELSON RES & DEV COMPANY (US) 1989-04-24 EP disclosed
EP-0257063-A1 COMPOSITIONS COMPRISING 1-SUBSTITUTED AZACYCLOALKANES AND THEIR USES. NELSON RES & DEV (US) 1988-03-02 EP disclosed
WO-1987004706-A1 COMPOSITIONS COMPRISING 1-SUBSTITUTED AZACYCLOALKANES AND THEIR USES NELSON RESEARCH AND DEVELOPMENT COMPANY (US) 1987-08-13 WO disclosed
JP-S58203902-A PROMOTOR FOR OCCURRENCE OF SIDE BRANCH OF MULBERRY FUJISAWA PHARMACEUT CO LTD 1983-11-28 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070191371-A1 HETEROCYCLIC MODULATORS OF PPAR PPARG, PPARD, PPARA SMN1; SMN2 4609/4885LMNA 2210/4885FFAR1 38/4885
US-20070004757-A1 INDOLINE DERIVATIVES SUBSTITUTED IN THE 6 POSITION, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS KDR, FLT1, EGFR SMN1; SMN2 4443/4885LMNA 2104/4885FFAR1 1282/4885
US-20110152077-A1 Active compound combinations BROX, ATL3, AKR7A2 SMN1; SMN2 2960/4885LMNA 2189/4885FFAR1 3037/4885
US-10246413-B2 Selective FKBP51 ligands for treatment of psychiatric disorders FKBP5, FKBP1A, FKBP3 SMN1; SMN2 792/4885LMNA 4560/4885FFAR1 1729/4885
US-20140005049-A1 ACTIVE COMPOUND COMBINATIONS BROX, ATL3, AKR7A2 SMN1; SMN2 2960/4885LMNA 2189/4885FFAR1 3037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.