SCHEMBL5855538

SCHEMBL5855538

Cc1cc(C)cc(C(=O)N[Ti](Cl)(Cl)(C2C=Cc3ccccc32)[SiH](c2ccccc2)c2ccccc2)c1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5853488 0.92 SMN1; SMN2 (0.41) POLBMEN1KMT2ALMNASMN1; SMN2
SCHEMBL5853329 0.89 ATM (0.32) MEN1KMT2ALMNA
SCHEMBL5853405 0.88 KMT2A (0.32) MEN1KMT2ALMNA
SCHEMBL5852876 0.88 MEN1 (0.34) POLBKDM4EMEN1KMT2ALMNA
SCHEMBL5853922 0.84 HPGD (0.36) POLBSMN1; SMN2
SCHEMBL5852797 0.84 TAS1R3 (0.34)
SCHEMBL5854622 0.83 MEN1 (0.31) MEN1KMT2A
SCHEMBL5853896 0.83 NR1H4 (0.36) MEN1KMT2ALMNASMN1; SMN2
SCHEMBL5853151 0.80 SIGMAR1 (0.31) MEN1KMT2A
SCHEMBL5852661 0.80 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed