SCHEMBL585558

SCHEMBL585558

Cc1cccc(N(c2cccc(C)c2C)c2cccc(C)c2C)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.46
ATM Q13315 1/20 0.46
CYP2A6 P11509 3/20 0.41
CYP1A2 P05177 2/20 0.41
TSHR P16473 3/20 0.40
ACHE P22303 1/20 0.40
ALDH1A1 P00352 5/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
MAPK1 P28482 1/20 0.38
MAPT P10636 2/20 0.36
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
CD44 P16070 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11808001 0.84 TRPA1 (0.42) TRPA1ATMCYP2A6CYP1A2TSHR
SCHEMBL13292338 0.84 ACHE (0.43) TRPA1ATMCYP2A6CYP1A2TSHR
SCHEMBL7890806 0.84 ALDH1A1 (0.38) TRPA1ATMCYP2A6CYP1A2TSHR
SCHEMBL5436537 0.81 TRPA1 (0.44) TRPA1ATMCYP2A6CYP1A2TSHR
SCHEMBL1911943 0.81 MAPT (0.48) TRPA1ATMCYP2A6CYP1A2TSHR
SCHEMBL30733276 0.81 MAPT (0.48) TRPA1ATMCYP2A6CYP1A2TSHR
SCHEMBL11192672 0.79 TRPA1 (0.42) TRPA1ATMCYP2A6CYP1A2TSHR
Hydrochloric Acid SCHEMBL2861142 0.79 MAPT (0.46) TRPA1ATMCYP2A6CYP1A2TSHR
SCHEMBL16860015 0.79 MAPT (0.46) TRPA1ATMCYP2A6CYP1A2TSHR
SCHEMBL9751387 0.79 TRPA1 (0.42) TRPA1ATMCYP2A6CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0138669-B1 PROCESS FOR THE PREPARATION OF SILANES FROM METHYLDICHLOROSILANE AND CHLOROSILANES RHONE-POULENC CHIMIE (FR) 1988-08-10 EP claimed
EP-0138670-B1 PROCESS FOR THE PREPARATION OF SILANES WITH A SI-H BOND BY REDISTRIBUTION RHONE-POULENC CHIMIE (FR) 1988-05-25 EP claimed
US-4746752-A QUATERNARY OR TERTIARY AMINE CATALYST RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-05-24 US claimed
US-4605543-A DISTRIBUTION AND DISPROPORTIONATION CATALYSIS RHONE-POULENC SPECIALITIES CHIMIQUES (FR) 1986-08-12 US claimed
EP-0138669-A2 Process for the preparation of silanes from methyldichlorosilane and chlorosilanes RHONE-POULENC CHIMIE (FR) 1985-04-24 EP claimed
EP-0138670-A2 Process for the preparation of silanes with a Si-H bond by redistribution RHONE-POULENC CHIMIE (FR) 1985-04-24 EP claimed
US-12416167-B2 Scuff resistant surface coverings TARKETT GDL (LU) 2025-09-16 US disclosed
US-20220363939-A1 One Component UV Curable Compositions And Methods For Making Same DVORCHAK ENTERPRISES LLC (US) 2022-11-17 US disclosed
US-11441048-B2 One component UV curable compositions and methods for making same DVORCHAK ENTERPRISES LLC (US) 2022-09-13 US disclosed
US-20220195739-A1 SCUFF RESISTANT SURFACE COVERINGS TARKETT GDL (LU) 2022-06-23 US disclosed
EP-3972838-A1 SCUFF RESISTANT SURFACE COVERINGS Tarkett GDL (LU) 2022-03-30 EP disclosed
EP-3902664-A1 DECORATIVE WALL OR FLOOR COVERING INSTALLATION METHOD Tarkett GDL (LU) 2021-11-03 EP disclosed
US-11078377-B2 Actinic radiation cured polyurethane coating for decorative surface coverings TARKETT GDL S.A. (LU) 2021-08-03 US disclosed
US-4035321-A Preparation of ultraviolet curable acrylated polymers CELANESE CORPORATION (US) 1977-07-12 US disclosed
US-4016334-A Method of applying high adhesion ultraviolet curable coatings and coated articles CELANESE CORPORATION (US) 1977-04-05 US disclosed
US-4008293-A ACRYLIC COPOLYMER, AMINOPLAST, BINDER PPG INDUSTRIES, INC. (US) 1977-02-15 US disclosed
US-3996394-A PHOTOPOLYMERIZATION UNION CARBIDE CORPORATION (US) 1976-12-07 US disclosed
US-3992276-A Unsaturated polyesters for ultraviolet curable coatings CELANESE CORPORATION (US) 1976-11-16 US disclosed
US-3992275-A Low gloss ultraviolet curable coatings utilizing α,α,α-trichlorotoluene as a photoinitiator CELANESE CORPORATION (US) 1976-11-16 US disclosed
US-3966572-A Photocurable low gloss coatings containing silica and acrylic acid UNION CARBIDE CORPORATION (US) 1976-06-29 US disclosed