Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5857383 | 0.86 | GSK3B (0.51) | MAPTNPSR1TP53GSK3BSLC7A5 | |
| SCHEMBL1185438 | 0.82 | GSK3B (0.44) | MAPTNPSR1GSK3BSLC7A5CA2 | |
| SCHEMBL15057163 | 0.81 | CA12 (0.39) | MAPTTP53GSK3BCA2CA12 | |
| SCHEMBL15933864 | 0.80 | MAPT (0.48) | MAPTNPSR1TP53GSK3BCA2 | |
| SCHEMBL16753610 | 0.79 | DAO (0.47) | MAPTGSK3BSLC7A5CA2CA12 | |
| SCHEMBL16355747 | 0.79 | DAO (0.55) | NPSR1TP53CA2CA12CA1 | |
| SCHEMBL5857494 | 0.77 | HPGDS (0.33) | NPSR1GSK3BSLC7A5CA2CA12 | |
| SCHEMBL5856765 | 0.76 | CA12 (0.49) | MAPTNPSR1TP53GSK3BCA2 | |
| SCHEMBL18152995 | 0.76 | GSK3B (0.44) | MAPTNPSR1GSK3BSLC7A5CA2 | |
| SCHEMBL15079197 | 0.74 | GSK3B (0.42) | GSK3BSLC7A5CA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115595-B2 | Carbapenem compounds | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2006-10-03 | — | — | US | disclosed |
| CN-1247582-C | Novel carbapenem compounds | DAINIPPON SUMITOMO PHARMACEUTI (JP) | 2006-03-29 | — | — | CN | disclosed |
| EP-1357123-B1 | Novel carbapenem, medical and antibacterial comprisisng the same, and uses thereof | SUMITOMO PHARMA (JP) | 2005-11-30 | — | — | EP | disclosed |
| EP-1535924-A1 | Novel carbapenem compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| CN-1489589-A | Novel carbapenem compounds | ס����ҩ��ʽ���� | 2004-04-14 | — | — | CN | disclosed |
| US-20040063683-A1 | Novel carbapenem compounds | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1357123-A1 | NOVEL CARBAPENEM COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2003-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063683-A1 | Novel carbapenem compounds | PTMS, PNISR, LRPPRC | MAPT 4420/4885NPSR1 1090/4885TP53 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.